Novel uses of apple seed extracts in cosmetic or pharmaceutical compositions
First Claim
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1. A topical cosmetic or pharmaceutical composition comprising at least one apple seed extract and at least one active ingredient selected from the group consisting of:
- organic, inorganic and modified inorganic light protection filters, protein hydrolyzates and their derivatives, mono-, oligo- and polysaccharides, and their derivatives, and α
-hydroxycarboxylic acids and α
-ketocarboxylic acids, and their ester, lactone or salt forms;
in a suitable carrier.
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Abstract
Novel topical cosmetic and pharmaceutical compositions containing apple core extracts, and novel uses of apple core extracts in topical cosmetic or pharmaceutical compositions.
15 Citations
11 Claims
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1. A topical cosmetic or pharmaceutical composition comprising at least one apple seed extract and at least one active ingredient selected from the group consisting of:
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organic, inorganic and modified inorganic light protection filters, protein hydrolyzates and their derivatives, mono-, oligo- and polysaccharides, and their derivatives, and α
-hydroxycarboxylic acids and α
-ketocarboxylic acids, and their ester, lactone or salt forms;
in a suitable carrier.
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- 2. A method of improving the mechanical stability of the skin, the skin appendages and the hair comprising adding apple seed extract to topical cosmetic or pharmaceutical compositions.
- 7. A method for stimulating the endogenous barrier function of the skin and the skin appendages comprising adding apple seed extracts to topical cosmetic or pharmaceutical compositions.
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10. A method for increasing the expression:
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of the keratin 5 (KRT5) having the Swiss-Prot number P13647, of the keratin 14 (KRT14) having the Swiss-Prot number P02533, of the keratin 10 (KRT10) having the Swiss-Prot number P13645, of the keratin 1 (KRT1) having the Swiss-Prot number P04264, of the gap junction protein beta 2 connexin 26 (CXB
2) having the Swiss-Prot number P29033,of the gap junction protein alpha 1 connexin 43 having the Swiss-Prot number P17302, of the hyaluronic acid receptor CD44 having the Swiss-Prot number P16070, of the fatty acid synthase (FAS) having the enzyme classification EC 2.3.1.85 and the Swiss-Prot number P49327, of the epidermal fatty acid binding protein FABE having the Swiss-Prot number Q01469, of the protein PSMD2 having the Swiss-Prot number Q13200 and of the DNA binding protein A (DBPA) having the Swiss-Prot number P16989, in cells of the skin and the skin appendages comprising adding apple seed extracts to topical cosmetic or pharmaceutical compositions.
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11. A method for inhibiting the expression of the bone proteoglycan II precursor (PGS2) having the Swiss-Prot number P07585 in cells of the skin and the skin appendages comprising adding apple seed extracts to topical cosmetic or pharmaceutical compositions.
Specification