Permselective structurally robust membrane material
First Claim
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1. A biocompatible multipolymer, having a backbone comprising:
- (a) about 10 to 45 wt % of at least one hard segment;
(b) about 55 to 90 wt % of soft segments, including;
(i) 5 to 25 wt %, of total soft segment weight, of an oxygen permeable soft segment;
(ii) 5 to 25 wt %, of total soft segment weight, of a hydrophilic soft segment; and
(iii) 50 to 90 wt %, of total soft segment weight, of a biostable, hydrophobic soft segment.
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Abstract
A biocompatible multipolymer, having a backbone comprising about 10 to 45 wt % of at least one hard segment and about 55 to 90 wt % of soft segments. The soft segments are divided into three groups, 5 to 25 wt %, of total soft segment weight, of an oxygen permeable soft segment; 5 to 25 wt %, of total soft segment weight, of a hydrophilic soft segment; and 50 to 90 wt %, of total soft segment weight, of a biostable, relatively hydrophobic soft segment.
15 Citations
17 Claims
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1. A biocompatible multipolymer, having a backbone comprising:
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(a) about 10 to 45 wt % of at least one hard segment;
(b) about 55 to 90 wt % of soft segments, including;
(i) 5 to 25 wt %, of total soft segment weight, of an oxygen permeable soft segment;
(ii) 5 to 25 wt %, of total soft segment weight, of a hydrophilic soft segment; and
(iii) 50 to 90 wt %, of total soft segment weight, of a biostable, hydrophobic soft segment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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- 12. A biocompatible hydrophilic segmented block multipolymer, being permeable to glucose, and wherein its water absorption and hydrophilic soft segment volume are less than 75% of its total dry polymer volume.
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17. A glucose sensor, which senses glucose by way of oxidation and which includes a membrane that is permselective of oxygen and glucose, said membrane comprising:
- A biocompatible multipolymer, having a backbone comprising a polycarbonate biostable, hydrophobic soft segment.
Specification