Electrotransport device having a reservoir housing having a flexible conductive element

• US 20050004506A1
• Filed: 03/30/2004
• Published: 01/06/2005
• Est. Priority Date: 03/31/2003
• Status: Active Grant

• Current Assignee: ALZA Corporation (Johnson & Johnson)
• Original Assignee: ALZA Corporation (Johnson & Johnson)
• Inventors: Gyory, J. Richard
• Granted Patent: US 8,224,435 B2
• Time in Patent Office: Days
• US Class Current: 604/20
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir

Abstract

This invention relates to an electrotransport device, which incorporates a flexible conductive element within the reservoir housing of the device, which permits electrical communication from within the housing to outside of the housing without the use of opening, which require various methods of sealing the opening against leaks and moisture.

Claims

1. An electrotransport device, comprising:

first and second electrodes;

a first reservoir adapted to receive an active agent formulation;

a second reservoir adapted to receive an electrolyte formulation,

said first reservoir being in communication with said electrode,

said second reservoir being in communication with said second electrode;

a power source;

electronic circuitry in communication with at least said first and second electrodes; and

a reservoir housing having an internal cavity adapted to receive said first electrode and said first reservoir, said reservoir housing including an integral conductive element having a first end in communication with said first reservoir and a second end that is disposed on the outside of said reservoir housing and extends therefrom, said second end of said conductive element being adapted to be operatively connected to said power source, whereby electrical communication between said first reservoir, said electronic circuitry and said power source is provided.

2. The electrotransport device of claim 1, wherein said power source is in communication with said electronic circuitry and said second end of said conductive element is adapted to be connected to said electronic circuitry.

3. The electrotransport device of claim 1, wherein said conductive element comprises a substantially planar member.

4. The electrotransport device of claim 2, wherein said conductive element is substantially flexible.

5. The electrotransport device of claim 1, wherein said conductive element includes a base member having a conductive coating disposed thereon.

6. The electrotransport device of claim 1, wherein said active agent formulation includes a therapeutic agent selected from the group consisting of anti-infectives, including antibiotics and antiviral agents;

analgesics, including fentanyl, sufentanil, remifentanil, buprenorphine and analgesic combinations;

anesthetics;

anorexics;

antiarthritics;

antiasthmatic agents;

anticonvulsants;

antidepressants;

antidiabetic agents;

antidiarrheals;

antihistamines;

anti-inflammatory agents;

antimigraine preparations;

antimotion sickness preparations such as scopolamine and ondansetron;

antinauseants;

antineoplastics;

antiparkinsonism drugs;

antipruritics;

antipsychotics;

antipyretics;

antispasmodics, including gastrointestinal and urinary;

anticholinergics;

sympathomimetrics;

xanthine derivatives;

cardiovascular preparations, including calcium channel blockers;

beta blockers;

beta-agonists, including dobutamine and ritodrine;

antiarrythmics;

antihypertensives, including atenolol;

ACE inhibitors such as ranitidine;

diuretics;

vasodilators, including general, coronary, peripheral, and cerebral;

central nervous system stimulants;

cough and cold preparations;

decongestants;

diagnostics;

hormones, including parathyroid hormone;

hypnotics;

immunosuppressants;

muscle relaxants;

parasympatholytics;

parasympathomimetrics;

prostaglandins;

proteins;

peptides;

psychostimulants;

sedatives; and

tranquilizers.