Implant with surface structure

• US 20050004526A1
• Filed: 02/27/2004
• Published: 01/06/2005
• Est. Priority Date: 08/31/2001
• Status: Active Grant

• Current Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Reinemann, Andreas
• Granted Patent: US 7,766,881 B2
• Time in Patent Office: Days
• US Class Current: 604/175
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61M 2039/0223 having means for anchoring the subcutaneous access site
• CPC Class Codes: A61M 2039/0261 Means for anchoring port to the body, or ports having a special shape or being made of a specific material to allow easy implantation/integration in the body
• CPC Class Codes: A61M 2039/0273 for introducing catheters into the body
• CPC Class Codes: A61M 2039/0276 for introducing or removing fluids into or out of the body
• CPC Class Codes: A61M 2039/0279 for introducing medical instruments into the body, e.g. endoscope, surgical tools
• CPC Class Codes: A61M 2039/0282 with implanted tubes connected to the port
• CPC Class Codes: A61M 39/0208 Subcutaneous access sites for injecting or removing fluids transcutaneous access sites A61M39/0247; implantable infusion devices A61M5/14276
• CPC Class Codes: A61M 39/0247 Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body peritoneal dialysis catheters A61M1/285; tracheostomy devices A61M16/0465; measuring pressure within the body A61B5/03; colostomy devices A61F5/445; gastrotomy feeding tubes A61J15/0015; means for fixing a feeding tube outside of the body A61J15/0053

Abstract

An implant with a surface structure on at least a portion of a surface of the implant, wherein the surface structure is selected to facilitate, improve and enhance ingrowth characteristics of the implant. A method of providing an implant with a selected surface structure is encompassed.

Claims

1. An implant having a surface, a surface structure on at least a portion of said surface, the surface structure improving ingrowth characteristics associated with the implant.

2. The implant as set forth in claim 1, wherein the implant comprises a non-biosorbable material.

3. The implant as set forth in claim 2, wherein said surface structure is provided in a region of the implant, wherein, after the implant has been implanted in a body, the surface structure is generally adjacent to the skin.

4. The implant as set forth in claim 1, wherein the surface structure exhibits a width of approximately 1 to 10 mm.

5. The implant as set forth in claim 1, wherein the surface structure exhibits a width of approximately 4 to 5 mm.

6. The implant as set forth in claim 1, wherein the surface structure generally encircles the implant.

7. The implant as set forth in claim 1, wherein the surface structure comprises one or more grooves.

8. The implant as set forth in claim 7, wherein the depth of said at least one or more grooves is approximately 0.1 to 10 times the average width of a type of cell adjacent to the groove after the implant is implanted.

9. The implant as set forth in claim 7, wherein the depth of said at least one or more grooves is approximately 0.3 to 5 times the average width of a type of cell adjacent to the groove after the implant is implanted.

10. The implant as set forth in claim 7, wherein the depth of the at least one groove is approximately 1 to 10 μ

m.

11. The implant as set forth in claim 7, wherein the depth of the at least one groove is approximately 3 to 4 μ

m.

12. The implant as set forth in claim 7, wherein the width of the at least one groove is in the range of approximately 1 to 10 μ

m.

13. The implant as set forth in claim 7, wherein the width of the at least one groove is in the range of approximately 4 to 5 μ

m.

14. The implant as set forth claim 7, wherein, if more than one groove is provided, the distance of the grooves from each other is approximately 2 to 20 μ

m.

15. The implant as set forth claim 7, wherein, if more than one groove is provided, the distance of the grooves from each other is approximately 10 μ

m.

17. The implant as set forth in claim 1, wherein at least two regions on the surface of the implant are provided with a surface structure.

18. The implant as set forth in claim 1, further comprising a holding structure with at least one passage.

19. The implant as set forth in claim 1, wherein the implant is a port body.

16. The implant as set forth in 7, wherein the ratio of the width of the groove to the depth of the groove is approximately 0.5 to 2.

20. A method for producing an implant for implanting in a living body, comprising the step of providing a surface structure on a surface of said implant, wherein the surface structure improves ingrowth characteristics associated with the implant.

21. The method as set forth in claim 20, wherein the surface structure is provided by turning a groove.

22. The method as set forth in claim 20, wherein the surface structure is provided by etching.