METHODS AND APPARATUS FOR A STENT HAVING AN EXPANDABLE WEB STRUCTURE

• US 20050004655A2
• Filed: 12/22/2003
• Published: 01/06/2005
• Est. Priority Date: 09/05/1998
• Status: Active Grant

• Current Assignee: Abbott Laboratories Limited (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Laboratories Limited (Abbott Laboratories Incorporated)
• Inventors: Seibold, Gerd, Von Oepen, Randolf
• Granted Patent: US 7,789,904 B2
• Time in Patent Office: Days
• US Class Current: 623/1.160
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91558 connected peak to peak

Abstract

Abstract of the Disclosure

The present invention provides a stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring web patterns, where each web patterns is composed of adjoining webs, and the web patterns are interconnected. Each adjoining web comprises a central section interposed between two lateral sections to form concave or convex configurations.

Claims

1. A stent comprising:

a tubular body having proximal and distal ends and a lumen extending therebetween, and a wall defining a web structure configured for expansion from a collapsed delivery configuration to an expanded deployed configuration,

wherein the web structure comprises a plurality of neighboring web patterns of alternating concavity that extend circumferentially around the wall, each web pattern including a plurality of arcuate webs interconnected by bends, neighboring web patterns interconnected by transition sections, wherein at least two of the transition sections are separated, around the circumference of the wall, by at least three arcuate webs; and

a coating on the web structure that comprises a therapeutic agent.

2. The stent of claim 1, wherein the therapeutic agent is chosen from the group consisting of therapeutic agents that retard thrombus formation, therapeutic agents that retard restenosis, and therapeutic agents for systemic or local delivery via the blood stream.

3. The stent of claim 1, wherein all of the transition sections are separated by at least three arcuate webs.

4. The stent of claim 1, wherein the transition sections define H-shaped structures.

5. The stent of claim 4, wherein at least some of the arcuate webs span two H-shaped structures.

6. The stent of claim 4, wherein at least one of the H-shaped structures is disposed at an angle relative to a longitudinal axis of the stent.

7. The stent of claim 1, wherein each arcuate web comprises at least one substantially straight section.

8. The stent of claim 7, wherein each arcuate web comprises three substantially straight sections.

9. The stent of claim 1, wherein the at least three arcuate webs define an S-shaped structure between interconnections to neighboring web patterns.

10. The stent of claim 1, wherein the stent is balloon expandable.

11. The stent of claim 1, wherein the stent comprises a deformable material.

12. The stent of claim 11, wherein the deformable material is chosen from the group consisting of stainless steel and titanium.

13. The stent of claim 1, wherein the stent is self- expanding.

14. The stent of claim 1, further comprising a radiopaque feature.

15. A stent comprising:

a tubular body having proximal and distal ends and a lumen extending therebetween, and a wall defining a web structure configured for expansion from a delivery configuration to a deployed configuration,

wherein the web structure comprises a plurality of neighboring web patterns of alternating concavity that extend circumferentially around the wall, each web pattern including a plurality of arcuate webs interconnected by bends, at least some of the neighboring web patterns interconnected by transition sections separated, around the circumference of the wall, by at least two bends; and

a coating on the web structure that comprises a therapeutic agent.

16. The stent of claim 15, wherein the therapeutic agent is chosen from the group consisting of therapeutic agents that retard thrombus formation, therapeutic agents that retard restenosis, and therapeutic agents for systemic or local delivery via the blood stream.

17. The stent of claim 15, wherein the neighboring web patterns are interconnected by transition sections separated, around the circumference of the wall, by at least four bends.

18. The stent of claim 15, wherein the transition sections define H-shaped structures.

19. The stent of claim 15, wherein at least some of the arcuate webs span two H-shaped structures.

20. The stent of claim 18, wherein at least one of the H-shaped structures is disposed at an angle relative to a longitudinal axis of the stent.

21. The stent of claim 15, wherein each arcuate web comprises at least one substantially straight section.

22. The stent of claim 21, wherein each arcuate web comprises three substantially straight sections.

23. The stent of claim 15, wherein transition sections interconnecting each web pattern to neighboring web patterns are separated by three arcuate webs that define an S-shaped structure.

24. The stent of claim 15, wherein the stent is balloon expandable.

25. The stent of claim 15, wherein the stent comprises a deformable material.

26. The stent of claim 25, wherein the deformable material is chosen from the group consisting of stainless steel and titanium.

27. The stent of claim 15, wherein the stent is self- expanding.

28. The stent of claim 15, further comprising a radiopaque feature.

29. Apparatus for supporting a vessel comprising:

a tube having proximal and distal ends and a lumen extending therebetween, the tube comprising a web structure having a collapsed state and an expanded state,

wherein the web structure comprises a plurality of neighboring web patterns of alternating concavity, each web pattern including a plurality of arcuate webs, at least some of the neighboring web patterns interconnected by transition sections that define apertures having three intercommunicating S-shaped openings; and

a coating on the web structure that comprises a therapeutic agent.

30. The apparatus of claim 29, wherein the therapeutic agent is chosen from the group consisting of therapeutic agents that retard thrombus formation, therapeutic agents that retard restenosis, and therapeutic agents for systemic or local delivery via the blood stream.

31. The apparatus of claim 29, wherein the transition sections define H-shaped structures that span adjacent pairs of arcuate webs.

32. The apparatus of claim 31, wherein at least one of the H-shaped structures is disposed at an angle relative to a longitudinal axis of the tube.

33. The apparatus of claim 29, wherein each arcuate web comprises at least one substantially straight section.

34. The apparatus of claim 33, wherein each arcuate web comprises three substantially straight sections.

35. The apparatus of claim 29, wherein transition sections interconnecting a web pattern to a neighboring web pattern are separated by three arcuate webs that define an S-shaped structure.

36. The apparatus of claim 29, wherein the tube is balloon expandable.

37. The apparatus of claim 29, wherein the tube comprises a deformable material.

38. The apparatus of claim 37, wherein the deformable material is chosen from the group consisting of stainless steel and titanium.

39. The apparatus of claim 29, wherein the tube is self-expanding.

40. The apparatus of claim 29, further comprising a radiopaque feature.

41. A stent comprising:

a tube having a web structure configured to transition between a contracted state and an expanded state,

wherein the web structure comprises a plurality of neighboring web patterns of alternating concavity, each web pattern including a plurality of arcuate webs interconnected by bends, neighboring web patterns interconnected by transition sections, at least some of the transition sections between any two neighboring web patterns being arranged around the circumference of the tube with a common orientation and offset by at least one intervening bend; and

a coating on the web structure that comprises a therapeutic agent.

42. The stent of claim 41, wherein the therapeutic agent is chosen from the group consisting of therapeutic agents that retard thrombus formation, therapeutic agents that retard restenosis, and therapeutic agents for systemic or local delivery via the blood stream.

43. The stent of claim 41, wherein the arcuate webs have a first width relative to the circumference of the tube, and the transition sections have a second width relative to the circumference of the tube, wherein the second width is about twice the first width.

44. The stent of claim 41, wherein the transition sections define H-shaped structures.

45. The stent of claim 44, wherein at least one of the H-shaped structures is disposed at an angle relative to a longitudinal axis of the tube.

46. The stent of claim 41, wherein each arcuate web comprises at least one substantially straight section.

47. The stent of claim 46, wherein each arcuate web comprises three substantially straight sections.

48. The stent of claim 41, wherein transition sections interconnecting each web pattern to neighboring web patterns are separated by at least three arcuate webs that define an S-shaped structure.

49. The stent of claim 41, wherein the stent is balloon expandable.

50. The stent of claim 41, wherein the stent comprises a deformable material.

51. The stent of claim 50, wherein the deformable material is chosen from the group consisting of stainless steel and titanium.

52. The stent of claim 41, wherein the stent is self- expanding.

53. The stent of claim 41, further comprising a radiopaque feature.

54. A stent comprising:

a tube having proximal and distal ends and a lumen extending from the proximal to the distal end, the tube comprising a web structure having a contracted delivery state and an expanded deployed state,

wherein the web structure includes a plurality of neighboring web patterns of alternating concavity, each web pattern including a plurality of arcuate webs, neighboring web patterns interconnected by transition sections that span pairs of adjacent arcuate webs, at least some of the transition sections of neighboring patterns offset by at least one additional arcuate web; and

a coating on the web structure that comprises a therapeutic agent.

55. The stent of claim 54, wherein the therapeutic agent is chosen from the group consisting of therapeutic agents that retard thrombus formation, therapeutic agents that retard restenosis, and therapeutic agents for systemic or local delivery via the blood stream.

56. The stent of claim 54, wherein the transition sections define H-shaped structures.

57. The stent of claim 56, wherein at least one of the H-shaped structures is disposed at an angle relative to a longitudinal axis of the stent.

58. The stent of claim 54, wherein each arcuate web comprises at least one substantially straight section.

59. The stent of claim 58, wherein each arcuate web comprises three substantially straight sections.

60. The stent of claim 54, wherein transition sections interconnecting a web pattern to a neighboring web pattern are separated by three arcuate webs that define an S-shaped structure.

61. The stent of claim 54, wherein the stent is balloon expandable.

62. The stent of claim 54, wherein the stent comprises a deformable material.

63. The stent of claim 62, wherein the deformable material is chosen from the group consisting of stainless steel and titanium.

64. The stent of claim 54, wherein the stent is self-expanding.

65. The stent of claim 54, further comprising a radiopaque feature.

66. Apparatus for supporting a vessel comprising:

a tubular body having a web structure defining a wall, the web structure configured to transition between a collapsed state and an expanded state,

wherein the web structure comprises a plurality of neighboring web patterns, each web pattern including a plurality of arcuate webs interconnected by bends, the arcuate webs of neighboring web patterns alternating between concave and convex forms relative to a longitudinal axis of the tubular body, the neighboring web patterns interconnected by H-shaped transition sections separated, around a circumference of the wall, by at least two bends; and

a coating on the web structure that comprises a therapeutic agent.

67. The apparatus of claim 66, wherein the therapeutic agent is chosen from the group consisting of therapeutic agents that retard thrombus formation, therapeutic agents that retard restenosis, and therapeutic agents for systemic or local delivery via the blood stream.

68. The apparatus of claim 66, wherein the arcuate webs have a first width relative to the circumference of the tubular body, and the H-shaped transition sections have a second width, relative to the circumference of the tubular body, about twice the first width.

69. The apparatus of claim 66, wherein at least one of the H-shaped transition sections is disposed at an angle relative to a longitudinal axis of the tubular body.

70. The apparatus of claim 66, wherein each arcuate web comprises at least one substantially straight section.

71. The apparatus of claim 70, wherein each arcuate web comprises three substantially straight sections.

72. The apparatus of claim 66, wherein the H-shaped transition sections interconnecting each web pattern to neighboring web patterns are separated by three arcuate webs that define an S-shaped structure.

73. The apparatus of claim 66, wherein the tubular body is balloon expandable.

74. The apparatus of claim 66, wherein the tubular body comprises a deformable material.

75. The apparatus of claim 74, wherein the deformable material is chosen from the group consisting of stainless steel and titanium.

76. The apparatus of claim 66, wherein the tubular body is self-expanding.

77. The apparatus of claim 66, further comprising a radiopaque feature.