Method and reagent for producing narrow, homogenous reagent stripes
First Claim
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1. A reagent composition for use in a slot-die-coating process, comprising:
- a viscosity between about 70 and about 130 mPa-s;
a surface tension between 30 and 50 mN/m; and
wherein said reagent composition is shear thinning and at least slightly thixotropic.
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Abstract
The present invention concerns a reagent coating mass which can be used in slot-die-coating of flat support materials in the manufacturing processes of test strips. Advantageously, the reagent mass of the invention exhibits certain superior rheological properties such as viscosity, surface tension and thixotropy. The reagent mass is preferably used to coat thin, narrow and homogeneous stripes of reagent material onto flat web material.
354 Citations
65 Claims
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1. A reagent composition for use in a slot-die-coating process, comprising:
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a viscosity between about 70 and about 130 mPa-s;
a surface tension between 30 and 50 mN/m; and
wherein said reagent composition is shear thinning and at least slightly thixotropic. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A process for producing a reagent layer on a solid support material, comprising the steps of:
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providing a solid support material;
moving said solid support material relative to a slot-die-coating head;
maintaining a defined distance between the surface of said solid support material and said slot-die-coating head;
depositing a shear thinning, at least slightly thixotropic reagent through said slot-die-coating head to create a continuous stripe of reagent on said solid support material, wherein said reagent has a viscosity of between about 70 and 130 mPa-s and a surface tension of between about 30 and 50 mN/m; and
drying the coated reagent stripe on said support material. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. An analytic test element comprising:
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a polymer web as a first solid support material; and
a reagent stripe coated onto said first solid support material, wherein said reagent stripe is coated on said support material as a shear thinning, at least slightly thixotropic composition having a viscosity between about 70 and 130 mPa-s and a surface tension of between about 30 and 50 mN/m. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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46. An analytic test element comprising:
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a polymer web as a first solid support material; and
a reagent stripe, wherein reagent stripe is deposited onto said first support material by a slot-die-coating process including the steps of;
moving said solid support relative to a slot-die-coating head;
maintaining a defined distance between said solid support material and said slot-die-coating head; and
depositing said reagent stripe as a shear thinning at least slightly thixotropic reagent composition having a viscosity between about 70 and 130 mPa-s and a surface tension of between 30 and 50 mN/m, on said solid support material. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65)
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Specification