Neurostimulation unit for immobilizing the heart during cardiosurgical operations

• US 20050010263A1
• Filed: 07/29/2002
• Published: 01/13/2005
• Est. Priority Date: 07/27/2001
• Status: Abandoned Application

• Current Assignee: Patrick Schauerte
• Original Assignee: Patrick Schauerte
• Inventors: Schauerte, Patrick
• Application Number:
  US10/485,040
• Publication Number:
  US 20050010263A1
• Time in Patent Office: Days
• US Class Current: 607/48
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/385 Devices for inducing an abnormal cardiac function, e.g. fibrillation

Abstract

The invention relates to a device for temporary reduction of heart movement during an operation, more particularly a heart operation, comprising a neurostimulation unit (20) for stimulation of the nerves (3) that slow down heart frequency, said unit including at least one electrode device (1) with at least one stimulation pole (2), wherein a control unit (19) connected to the neurostimulation device (20) is provided. Said control device has a first input device (26) for inputting a degree of immobilization and is configured to influence the operating state of the neurostimulation device (20) depending on the previously set degree of immobilization.

Claims

1. A device for temporarily reducing the movement of the heart during surgery, comprising:

a neurostimulation device for stimulating nerves that slow down the heart rate, having at least one electrode device with at least one stimulation pole and

a control unit being connected to the neurostimulation device having a first input device for preselecting a degree of electric immobilization of the heart and being arranged for patient specifically influencing the operation mode of the neurostimulation device as a function of the preselected degree of electric immobilization, wherein the first input device is arranged for variably preselecting the degree of electric immobilization during operation.

2. The device according to claim 1, wherein the stimulation pole of the electrode device has an effective stimulation area of 1 to 100 mm².

3. The device according to claim 1 wherein the electrode device comprises at least two stimulation poles for bipolar stimulation that are arranged spatially separate.

4. The device according to claim 3, wherein the stimulation poles have a distance between each other that is between about 2 and about 10 mm.

5. The device according to claim 1, wherein the electrode device inserts into a nerve plexus.

6. The device according to claim 1, wherein the electrode device comprises at least one locking device for securing the electrode device on a location selected from the group consisting of a nerve plexus, a blood vessel, and a combination thereof.

7. The device according to claim 6, wherein the at least one locking device comprises at least one fastening device with at least two arms for securely clamping the electrode device and wherein at least one stimulation pole is arranged in an area of a free end of a forceps arm.

8. The device according to claim 6, wherein the locking device comprises at least one suction device having at least one suction opening for fastening the electrode device to human tissue by employment of a vacuum.

9. The device according to claim 8, wherein the stimulation pole is situated in an area of the suction opening.

10. The device according to claim 6, wherein the locking device comprises at least one supply channel for tissue adhesive with at least one mouth opening for securing the electrode device with the adhesive in the area of the mouth opening.

11. The device according to claim 10, wherein the stimulation pole is situated in the area of the mouth opening.

12. The device according to claim 1, wherein the electrode device is a screw electrode.

13. The device according to claim 1, wherein the electrode device comprises a shielding device that is provided for the stimulation pole to prevent unwanted stimulation of cardiac tissue.

14. The device according to claim 1, wherein the neurostimulation device comprises a pulse generating unit that is connected to the electrode device and is also connected to the control unit for triggering purposes.

15. The device according to claim 14, wherein the pulse generating unit generates pulses that have a characteristic selecting from the group consisting of a duration between 0 and 20 ms, a stimulation frequency between 0 and 1000 Hz, a stimulation voltage between 1 and 100 V, and any combinations thereof.

16. The device according to claim 14 wherein the pulse generating unit provides continuous stimulation.

17. The device according to claim 14 wherein the pulse generating unit provides intermittent stimulation, generating short bursts of high-frequency pulses.

18. The device according to claim 17, further comprising a first detection unit that is connected to the control unit for detecting a refractory phase of the heart, wherein the control unit operates the pulse generating unit as a function of a state of the first detection unit.

19. The device according to claim 18, wherein the first detection unit comprises at least one sensing electrode that is formed by the electrode device.

20. The device according to one of the claim 1, further comprising at least one second detection unit connected to the control unit, for detecting at least one biological or human measured variable, wherein the control unit influences the neurostimulation device as a function of a state of the second detection unit.

21. The device according to claim 1, further comprising a movement reducing device that is connected to the control unit, wherein the control unit influences an operating state of the movement reducing device.

22. The device according to claim 21, wherein the control unit is in an operating mode selected from the group consisting of a first operating mode, a second operating mode, and a combination thereof, and wherein:

the first operating mode, the control unit influences an operating state of the movement reducing device as a function of an operating state of the neurostimulation device and, and in a second operating mode, the control unit separately influences the operating state of the movement reducing device and the neurostimulation device.

23. The device according to claim 22, wherein the control unit comprises a switching device for switching between the first operating mode and the second operating mode.

24. The device according to claim 21 wherein the movement reducing device comprises a device selected from the group consisting of a pump device for supporting cardiac function, a stabilization device for stabilizing the cardiac wall, and a combination thereof.

25. The device according to claim 21, wherein the control unit controls the operating state of the movement reducing device as a function of information selected from the group consisting of a type of stimulation of the neurostimulation device, a stimulation intensity of the neurostimulation device, and a combination thereof.

26. The device according to claim 21, further comprising a second input device that is connected to the control unit for storing at least one patient-specific data record that is representative of a course of a stimulation dose and a immobilization effect, and wherein the control unit influences the neurostimulation device as a function of the patient data record.

27. The device according to claim 21, further comprising a heart rate detection device that is connected to the control unit for detecting a heart rate signal that is representative of the actual heart rate,

wherein the control unit influences a device selected from the group consisting of the neurostimulation device the movement reducing device and a combination thereof, as a function of a state of the heart rate detection device.

28. The device according to claim 27, further comprising a third input device that is connected to the control unit for input of a setpoint heart rate,

wherein the control unit influences a device selected from the group consisting of the neurostimulation device the movement reducing device and a combination thereof, as a function of the state of the heart rate detection device and the third input device.

29. The device according to claim 21, further comprising a cardiac output detection device that is connected to the control unit for detecting a cardiac output signal that is representative of the actual cardiac output,

wherein the control unit influences a device selected from the group consisting of the neurostimulation device, the movement reducing device, and a combination thereof, as a function of the state of the cardiac output detection device.

30. The device according to claim 29, further comprising a fourth input device that is connected to the control unit for input of a setpoint cardiac output,

wherein the control device influences a device selected from the group consisting of the neurostimulation device the movement reducing device, and a combination thereof, as a function of the state of the cardiac output detection device and the fourth input device.

31. The device according to claim 21, wherein the movement reducing device comprises a pump unit for supporting heart function, and wherein the electrode device of the neurostimulation device is situated on the pump unit.

32. The device according to claim 31, wherein the stimulation pole is situated on the pump unit.

33. The device according to claim 1, wherein the stimulation pole of the electrode device has an effective stimulation area of 4 to 9 mm².

34. The device according to claim 14, wherein the pulse generating unit generates pulses that have a characteristic selected from the group consisting of a duration between 0.05 to 5 ms, a stimulation frequency between 2 to 100 Hz, a stimulation voltage between 1 and 100 V, and any combinations thereof.

54. The device according to claim 21, further comprising a device for detecting a cardiac output signal representative of the patient'"'"'s actual cardiac output;

wherein an application is controlled as a function of said detected cardiac output signal, and wherein the application is selected from the group consisting of stimulation to the nerves that slow down the heart rate, operation of the movement reducing device, and a combination thereof.

35. A method for temporarily reducing the movement of a patient'"'"'s heart during surgery, comprising:

pre-selecting a degree of electric immobilization of the heart; and

providing stimulation to nerves that slow down a heart rate,

wherein said stimulation is patient specifically influenced as a function of the pre-selected degree of electric immobilization, and the pre-selected degree of electric immobilization is variable during operation.

36. The method according to claim 35, wherein the stimulation to the nerves is bipolar stimulation.

37. The method according to claim 35, wherein the stimulation to the nerves is provided to a nerve plexus of the nerves.

38. The method according to claim 37, further comprising inserting an electrode device into the nerve plexus.

39. The method according to claim 35, further comprising securing an electrode device on a location selected from the group consisting of a nerve plexus, a blood vessel, and a combination thereof, wherein the stimulation to the nerves is provided by the electrode device.

40. The method according to claim 39, wherein the electrode device is secured on the location by a technique selected from the group consisting of applying a clamping force, applying a suction force, applying a tissue adhesive, applying a screw connection, and any combinations thereof.

41. The method according to claim 35, further comprising shielding tissue surrounding a location of the stimulation to the nerves to prevent unwanted stimulation of cardiac tissue.

42. The method according to claim 35, wherein the stimulation to the nerves is provided by stimulation pulses, wherein the stimulation pulses have a characteristic selected from the group consisting of a duration between 0 and 20 ms, a stimulation frequency between 0 and 1000 Hz, a stimulation voltage between 1 and 100 V, and any combinations thereof.

43. The method according to claim 35, wherein the stimulation to the nerves is provided by continuous stimulation.

44. The method according to claim 35, wherein the stimulation to the nerves is provided by intermittent stimulation, wherein the intermittent stimulation includes generating short bursts of high-frequency pulses.

45. The method according to claim 35, further comprising detecting a refractory phase of the heart, wherein the stimulation to the nerves is provided as a function of the detected refractory phase of the heart.

46. The method according to claim 35, further comprising detecting at least one biological or human measured variable, wherein the stimulation to the nerves is provided as a function of the detected biological or human measured variable.

47. The method according to claim 35, further comprising:

providing a movement reducing device; and

providing an operating mode selected from the group consisting of a first operating mode, a second operating mode, and a combination thereof, wherein in the first operating mode, an operating state of the movement reducing device is influenced as a function of the stimulation to the nerves, and in the second operating mode, an operating state of the movement reducing device is influenced separately from the stimulation to the nerves.

48. The method according to claim 47, further comprising switching between the first operating mode and the second operating mode.

49. The method according to claim 35, further comprising providing a movement reducing device, wherein the movement reducing device is selected from the group consisting of a pump device for supporting cardiac function, a stabilization device for stabilizing the cardiac wall, and a combination thereof.

50. The method according to claim 49, further comprising controlling an operating state of the movement reducing device as a function of information selected from the group consisting of a type of the stimulation to the nerves, a stimulation intensity of the stimulation to the nerves, and a combination thereof.

51. The method according to claim 35, wherein the stimulation to the nerves is provided as a function of at least one patient-specific patient data record, wherein the patient-specific patient data record is representative of a patient-specific course of a stimulation dose and an immobilization effect.

52. The method according to claim 35, further comprising:

detecting a heart rate signal representative of the patient'"'"'s actual heart rate; and

controlling an application as a function of said detected heart rate signal, wherein the application is selected from the group consisting of the stimulation to the nerves, operation of a movement reducing device, and a combination thereof.

55. The method according to claim 35, further comprising:

selecting a setpoint cardiac output; and

controlling an application as a function of said selected setpoint cardiac output, wherein the application is selected from the group consisting of the stimulation to the nerves, operation of a movement reducing device, and a combination thereof.

53. The method according to claim 53, further comprising:

selecting a setpoint heart rate; and

controlling the application as a function of said selected setpoint heart rate.