Implantable intraluminal device and method of using same in treating aneurysms

• US 20050010281A1
• Filed: 08/04/2004
• Published: 01/13/2005
• Est. Priority Date: 07/09/2001
• Status: Active Grant

• Current Assignee: Stryker Corporation
• Original Assignee: Surpass Medical Ltd. (Stryker Corporation)
• Inventors: Yodfat, Ofer, Grad, Ygael, Lieber, Baruch, Nishri, Boaz
• Granted Patent: US 7,306,624 B2
• Time in Patent Office: Days
• US Class Current: 623/1.390
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/821 Ostial stents
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2250/0023 differing in porosity
• CPC Class Codes: Y10S 623/909 Method or apparatus for assembling prosthetic

Abstract

A method for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.

Claims

1. A method for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising:

providing a first mesh-like tube of bio-compatible material, said first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm;

inserting said first mesh-like tube into the source blood vessel and the first branch vessel; and

securing said first mesh-like tube to at least one of said source blood vessel and said first branch vessel,

whereby blood flowing from said source blood vessel flows without undue impedance to said first branch vessel and said second branch vessel while being skewed away from said aneurysm.

2. A method according to claim 1, further comprising

providing a second mesh-like tube of bio-compatible material, said second mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm;

and

inserting said second mesh-like tube into the source blood vessel and the second branch vessel.

3. A method according to claim 1, wherein said first mesh-like tube includes windows having an inscribed diameter of 30-480 μ

m.

4. A method according to claim 1, wherein said first mesh-like tube includes windows having an inscribed diameter of 50-320 μ

m.

5. A method according to claim 1, wherein said first mesh-like tube is constituted of a plurality of filaments of bio-compatible material.

6. A method according to claim 5, wherein at least most of said plurality of filaments are of circular cross-section having a diameter of 10-60 μ

m.

7. A method according to claim 5, wherein at least most of said plurality of filaments are of circular cross-section having a diameter of 20-40 μ

m.

8. A method according to claim 5, wherein at least most of said plurality of filaments are of rectangular cross-section having a circumference of 40-180 μ

m.

9. A method according to claim 1, wherein said first mesh-like tube is formed of 24-144 filaments of bio-compatible material.

10. A method according to claim 1, wherein said first mesh-like tube is formed of 62-120 filaments of bio-compatible material.

11. A method according to claim 1, wherein said first mesh-like tube exhibits a porosity index of 55-80%.

12. A method according to claim 1, wherein said first mesh-like tube exhibits a porosity index of 60-75%.

13. A method for reducing blood flow to an aneurysm occupying the basal apex of a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising:

providing a mesh-like tube of bio-compatible material, said mesh-like tube exhibiting a porosity index pre-selected to skew blood flow away from the basal apex aneurysm;

inserting said first mesh-like tube into the source blood vessel and the first branch vessel; and

securing said first mesh-like tube to at least one of said source blood vessel and said first branch vessel,

whereby blood flowing from said source blood vessel flows without undue impedance to said first branch vessel and said second branch vessel while being skewed away from said basal apex aneurysm.

14. An intraluminal device implantable in the vicinity of a blood vessel bifurcation, the bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the aneurysm being located proximate to the bifurcation, the device comprising:

a mesh-like tube of bio-compatible material having an expanded condition in which the tube diameter is slightly larger than the diameter of the blood vessel in which it is to be implanted, said mesh-like tube having a length sufficient to be anchored to both the source blood vessel and the first branch vessel thereby straddling the opening of the second branch vessel;

said mesh-like tube also having a contracted condition wherein it is sufficiently flexible so as to be easily manipulatable through the blood vessel so as to be placed proximate to the bifurcation;

said mesh-like tube being dimensioned and configured to have in its implanted condition a porosity index of 55-80% so as to skew the flow of blood away from the aneurysm sufficiently to decrease the possibility of rupture of said aneurysm but not to unduly reduce the blood flow to said second branch vessel to a degree likely to cause significant damage to tissues supplied with blood by such second branch vessel.

15. An intraluminal device according to claim 14, wherein said mesh-like tube is dimensioned and configured to have in its implanted condition a porosity index of 60-75%.

16. An intraluminal device according to claim 14, wherein said mesh-like tube includes windows having an inscribed diameter of 30-480 μ

m in its implanted condition.

17. An intraluminal device according to claim 14, wherein said mesh-like tube includes windows having an inscribed diameter of 50-320 μ

m in its implanted condition.

18. An intraluminal device according to claim 14, wherein said mesh-like tube is constituted of a plurality of filaments of bio-compatible material.

19. An intraluminal device according to claim 18, wherein at least most of said plurality of filaments are of circular cross-section having a diameter of 10-50 μ

m.

20. An intraluminal device according to claim 18, wherein at least most of said plurality of filaments are of circular cross-section having a diameter of 20-40 μ

m.

21. An intraluminal device according to claim 18, wherein at least most of said plurality of filaments are of rectangular cross-section having a circumference of 40-200 μ

m.

22. An intraluminal device according to claim 14, said mesh-like tube is formed of 24-144 filaments of bio-compatible material.

23. An intraluminal device according to claim 14, wherein said mesh-like tube is formed of 62-120 filaments of bio-compatible material.

24. An intraluminal device according to claim 14, wherein said mesh-like tube is constituted of a plurality of filaments of bio-compatible material extending helically in an interlaced manner so as to form a braided tube, said mesh-like tube being said braided tube.

25. An intraluminal device according to claim 14, wherein said mesh-like tube is one of a woven tube, a knitted tube and a braided tube.