Sampling syringe unit, sampling device and sampling method for sampling blood or body fluid

• US 20050015019A1
• Filed: 07/18/2003
• Published: 01/20/2005
• Est. Priority Date: 07/18/2003
• Status: Abandoned Application

• Current Assignee: Yamatake Corporation
• Original Assignee: Yamatake Corporation
• Inventors: Yoshida, Hiroyuki, Miyagishi, Tetsuya, Honda, Nobuaki
• Application Number:
  US10/623,254
• Publication Number:
  US 20050015019A1
• Time in Patent Office: Days
• US Class Current: 600/576
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150969 Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
• CPC Class Codes: A61B 5/15109 Fully automatically triggered, i.e. the triggering does not require a deliberate action by the user, e.g. by contact with the patient's skin
• CPC Class Codes: A61B 5/15115 Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
• CPC Class Codes: A61B 5/1513 comprising linear sliding guides comprising tooth-shaped elements A61B5/15132
• CPC Class Codes: A61B 5/15146 Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means. multiple simultaneous cutting or piercing A61B5/150977
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/15192 comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/6824 Arm or wrist

Abstract

A sampling syringe unit includes a syringe base for defining a chamber in cooperation with a diaphragm, a needle protruding substantially perpendicularly from the syringe base and communicating with the chamber, and a protective member which, in a normal state, is elastically urged to be located more outward than the tip of the needle. A sampling device to which the sampling syringe unit is removably attached includes a first actuator for displacing the syringe base, and a second actuator for displacing the diaphragm and then releasing the displacing force to restore the diaphragm and thereby cause a suction pressure to be produced in the chamber.

Claims

1. A sampling syringe unit for sampling blood or body fluid, comprising:

a syringe base;

a diaphragm attached to one surface of said syringe base, for defining a chamber in cooperation with said syringe base;

a hollow tubular needle protruding substantially perpendicularly from a surface of said syringe base opposite to the surface on which said diaphragm is arranged, and communicating with the chamber; and

a protective member having an aperture for passing said needle therethrough, said protective member facing the surface of said syringe base from which said needle protrudes and movable toward and away from said syringe base, wherein in a normal state, said protective member is located more outward than a tip of said needle.

2. The sampling syringe unit according to claim 1, wherein said sampling syringe unit is a disposable type removably attached to a sampling device.

3. The sampling syringe unit according to claim 1, wherein said needle protrudes from a central portion of said syringe base and has an outer diameter of 0.1 mm or less.

4. The sampling syringe unit according to claim 1, wherein said syringe base has electrodes arranged in a communication passage connecting the chamber and said needle for examining a substance sampled through said needle.

5. The sampling syringe unit according to claim 4, wherein said electrodes are arranged in a portion of the communication passage extending parallel with said diaphragm.

6. A sampling device for sampling blood or body fluid, comprising:

a housing unit to which the sampling syringe unit according to claim 1 is removably attached in such a manner that the surface of the syringe base on which the needle is arranged faces outward;

a first actuator arranged in said housing unit, for displacing the syringe base of the sampling syringe unit attached to said housing unit in a direction toward the surface of the syringe base on which the needle is arranged; and

a second actuator arranged in said housing unit and driven in association with said first actuator, for displacing the diaphragm in a direction toward the surface of the syringe base on which the needle is arranged, and then releasing the displacing force to restore the diaphragm and thereby cause a suction pressure to be produced in the chamber.

7. A sampling device for sampling blood or body fluid, comprising:

a housing unit to which the sampling syringe unit according to claim 1 is removably attached in such a manner that the surface of the syringe base on which the needle is arranged faces outward;

an actuator arranged in said housing unit, for displacing the syringe base of the sampling syringe unit attached to said housing unit in a direction toward the surface of the syringe base on which the needle is arranged; and

a deformation control member for deforming the diaphragm as the syringe base is displaced, to cause a suction pressure to be produced in the chamber, and then maintaining a deformed state of the diaphragm.

8. The sampling device according to claim 6 or 7, further comprising a controller incorporated in said housing unit for controlling operation timing of said actuators/actuator.

9. A method of sampling blood or body fluid, comprising:

attaching the sampling devices according to claim 8 to a subject; and

sequentially driving the sampling devices to sample blood or body fluid from the subject at different times.