Reduced volume electrochemical sensor

• US 20050023136A1
• Filed: 06/02/2004
• Published: 02/03/2005
• Est. Priority Date: 06/06/2003
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: Leach, Christopher Philip, Beck, Erica Mary
• Granted Patent: US 7,462,265 B2
• Time in Patent Office: Days
• US Class Current: 204/403.10
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

An electrochemical glucose sensor comprising a base substrate, a conductive layer disposed on said base substrate, where said conductive layer comprises a reference electrode and at least two working electrodes; an insulation layer disposed on a part of said conductive layer, a reagent layer disposed on said working electrodes and on at least a part of said reference electrode, an adhesive layer disposed on a portion of said reagent layer and conductive layer wherein said adhesive layer substantially defines an area of said reference electrode which can be wetted by a liquid sample and said insulation layer substantially defines an area of said working electrodes which can be wetted by a liquid sample.

Claims

1. An electrochemical glucose sensor comprising:

a base substrate;

a conductive layer disposed on said base substrate, and wherein said conductive layer comprises a reference electrode and at least two working electrodes;

an insulation layer disposed on at least a part of said conductive layer;

a reagent layer disposed on said working electrodes and on at least a part of said reference electrode;

an adhesive layer disposed on a portion of said reagent layer and conductive layer;

wherein said adhesive layer substantially defines an area of said reference electrode which can be wetted by a liquid sample; and

said insulation layer substantially defines an area of said working electrodes which can be wetted by a liquid sample.

2. An electrochemical glucose sensor of claim 1 further comprising:

a hydrophilic layer disposed on said adhesive layer to form a sample receiving chamber, whereby a liquid sample can wick into said sample receiving chamber.

3. An electrochemical glucose sensor of claim 1, wherein said insulation layer further comprises:

a T-shaped aperture having a proximal rectangle and a distal rectangle;

wherein said proximal rectangle has a width and is contiguous with said distal rectangle which also has a width;

said proximal rectangle substantially overlapping with said reference electrode;

said distal rectangle substantially overlapping with said working electrodes; and

said width of said proximal rectangle is greater than said width of said distal rectangle.

4. An electrochemical glucose sensor comprising:

a base substrate;

a conductive layer disposed on said base substrate, and wherein said conductive layer comprises a reference electrode and at least two working electrodes;

an insulation layer disposed on said conductive layer;

wherein said insulation layer has at least one registration guide, an adhesive layer disposed on a portion of said insulation layer; and

whereby said registration guide facilitates the alignment of said adhesive layer being disposed on said insulation layer.

5. An electrochemical glucose sensor of claim 4 wherein said registration guide further comprises a rectangular aperture within said insulation layer.

6. An electrochemical glucose sensor comprising:

a base substrate;

a conductive layer disposed on said base substrate, and wherein said conductive layer comprises a reference electrode and at least two working electrodes;

an insulation layer disposed on said conductive layer;

an adhesive layer disposed on a portion of said insulation layer;

wherein said adhesive layer has at least one singulation guide, and

whereby said singulation guide facilitates the singulation of said electrochemical glucose sensor by reducing the amount of adhesive build up in a machine having a means for singulation.