Method and apparatus for 4-dimensional image warping
First Claim
1. A method of atlas mapping rigidly aligned temporally successive N-1 dimensional images of a subject, which form a N dimensional representation of the subject, the method comprising:
- generating a N dimensional template;
generating attribute vectors for a plurality of points of the N dimensional representation of the subject and of the N dimensional template, the plurality of points corresponding to a plurality of temporally successive voxels of the N dimensional representation of the subject and of the N dimensional template;
evaluating the generated attribute vectors to identify points in the N dimensional template that correspond to respective points in the N dimensional representation of the subject; and
deforming the N dimensional template to the N dimensional representation of the subject according to relative positions of the respective corresponding points of the N dimensional representation of the subject and of the N dimensional template.
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Abstract
A method of atlas mapping and an apparatus for image mapping are provided. The method includes generating a four dimensional template, linearly transforming the four dimensional representation of a subject to the four dimensional template, generating attribute vectors for a plurality of points of the linearly transformed four dimensional representation of the subject and of the four dimensional template, the plurality of points consisting of a plurality of temporally successive voxels of the four dimensional representation of the subject and of the four dimensional template, evaluating the generated attribute vectors to identify points in the four dimensional template that correspond to the four dimensional representation of the subject, and deforming the four dimensional template to the four dimensional representation of the subject according to relative positions of the corresponding points of the linearly transformed four dimensional representation of the subject and of the four dimensional template.
21 Citations
23 Claims
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1. A method of atlas mapping rigidly aligned temporally successive N-1 dimensional images of a subject, which form a N dimensional representation of the subject, the method comprising:
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generating a N dimensional template;
generating attribute vectors for a plurality of points of the N dimensional representation of the subject and of the N dimensional template, the plurality of points corresponding to a plurality of temporally successive voxels of the N dimensional representation of the subject and of the N dimensional template;
evaluating the generated attribute vectors to identify points in the N dimensional template that correspond to respective points in the N dimensional representation of the subject; and
deforming the N dimensional template to the N dimensional representation of the subject according to relative positions of the respective corresponding points of the N dimensional representation of the subject and of the N dimensional template. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method of atlas mapping of rigidly aligned temporally successive three dimensional images of a subject, which form a four dimensional representation of the subject, the method comprising:
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generating a four dimensional template;
linearly transforming the four dimensional representation of the subject to the four dimensional template;
determining attribute vectors for a plurality of points of the linearly transformed four dimensional representation of the subject and of the four dimensional template, the plurality of points corresponding to a plurality of temporally successive voxels of the four dimensional representation of the subject and of the four dimensional template;
establishing correspondences between the four dimensional representation of the subject and the four dimensional template according to similarities between the determined attribute vectors the plurality of points of the linearly transformed four dimensional representation of the subject and of the four dimensional template;
deforming a plurality of four dimensional subvolumes located around respective points of the four dimensional template according to relative positions of the corresponding points of the linearly transformed four dimensional representation of the subject and of the four dimensional template to provide a deformed four dimensional template; and
smoothing the deformed four dimensional template. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15)
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16. A method of atlas mapping of temporally successive three dimensional images of a subject, which form a four dimensional representation of the subject, the method comprising:
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generating a four dimensional template;
establishing correspondences between neighboring three dimensional images of the subject according to determined attribute vectors for the plurality of voxels of plural temporally successive three dimensional images of the subject;
rigidly aligning the plural temporally successive three dimensional images of the subject according to the established correspondences between the neighboring three dimensional images of the subject, the rigidly aligned plural temporally successive three dimensional images being the four dimensional representation of the subject;
linearly transforming the four dimensional representation of the subject to the four dimensional template;
establishing respective correspondences between the four dimensional representation of the subject and the four dimensional template according to similarities of determined attribute vectors for a plurality of points of the linearly transformed four dimensional representation of the subject and of the four dimensional template, the plurality of points consisting of a plurality of temporally successive voxels of the four dimensional representation of the subject and of the four dimensional template;
deforming four dimensional subvolumes located around the points of the four dimensional template according to relative positions of points of the four dimensional representation of the subject and the respective points of the four dimensional template to provide a deformed four dimensional template; and
smoothing the deformed four dimensional template. - View Dependent Claims (17, 18, 19)
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20. A method of atlas mapping of temporally successive three dimensional images of a subject, which form a four dimensional representation of subject, the method comprising the steps of:
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a) generating a four dimensional template representing a reference and corresponding to the four dimensional representation of the subject;
b) determining spatial attribute vectors for a plurality of voxels for plural temporally successive three dimensional images of the subject;
c) selecting respective voxels based on the determined spatial attribute vectors for the plurality of voxels;
d) establishing correspondences between neighboring three dimensional images of the subject according to the selected, respective voxels for the plural temporally successive three dimensional images of the subject;
e) rigidly aligning the plural temporally successive three dimensional images of the subject according to the established correspondences between the neighboring three dimensional images of the subject to form the four dimensional representation of the subject;
f) linearly transforming the four dimensional representation of the subject to the four dimensional template;
g) determining spatiotemporal attribute vectors for a plurality of points of the linearly transformed four dimensional representation of the subject and the four dimensional template, the plurality of points consisting of a plurality of temporally successive voxels of the four dimensional representation of the subject and of the four dimensional template;
h) selecting a plurality of subject active points from among the points of the linearly transformed four dimensional representation of the subject, and a plurality of template active points from among the points of the four dimensional template according to the determined spatiotemporal attribute vectors;
i) establishing correspondences between the four dimensional representation of the subject and the four dimensional template according to similarities between the selected plurality of subject active points and template active points;
j) deforming a plurality of four dimensional subvolumes, located around respective, selected ones of the template active points according to relative positions of respective, selected ones of the subject active points to provide a deformed four dimensional template, when respective correspondences are established between the respective, selected active points of the linearly transformed four dimensional representation of the subject and the four dimensional template;
k) smoothing the deformed four dimensional template using a Gaussian filter; and
l) repeating the steps g through j, while increasing a number of the selected active points in the linearly transformed four dimensional representation of the subject and the deformed four dimensional template. - View Dependent Claims (21, 22)
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23. A computer readable carrier including program code for causing a computer to implement a method of atlas mapping rigidly aligned temporally successive N-1 dimensional images of a subject, which form a N dimensional representation of the subject, the method comprising:
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generating a N dimensional template;
generating attribute vectors for a plurality of points of the N dimensional representation of the subject and of the N dimensional template, the plurality of points corresponding to a plurality of temporally successive voxels of the N dimensional representation of the subject and of the N dimensional template;
evaluating the generated attribute vectors to identify points in the N dimensional template that correspond to respective points in the N dimensional representation of the subject; and
deforming the N dimensional template to the N dimensional representation of the subject according to relative positions of the respective corresponding points of the N dimensional representation of the subject and of the N dimensional template.
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Specification