Method and device for enhancing transdermal agent flux
First Claim
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1. A microprojection for insertion into a biological surface, comprising:
- a microprojection member having interior and exterior surfaces, said exterior surface substantially enclosing said interior surface; and
a biocompatible coating disposed on said interior surface, said microprojection member being adapted to substantially restrict contact of said coating with the body surface during insertion of said microprojection member into the body surface.
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Abstract
A porous microprojection member for insertion into biological tissue surrounded by interstitial fluid having a wall that includes interior and exterior surfaces, the exterior surface substantially enclosing the interior surface; and a biocompatible coating disposed on the interior surface, the microprojection member being adapted to substantially restrict contact of the coating with the tissue during insertion of the microprojection member into the tissue, the microprojection member having sufficient porosity to allow migration of the interstitial fluid through the wall of the microprojection member.
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Citations
50 Claims
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1. A microprojection for insertion into a biological surface, comprising:
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a microprojection member having interior and exterior surfaces, said exterior surface substantially enclosing said interior surface; and
a biocompatible coating disposed on said interior surface, said microprojection member being adapted to substantially restrict contact of said coating with the body surface during insertion of said microprojection member into the body surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A microprojection for insertion into biological tissue, the tissue being surrounded by interstitial fluid, the microprojection comprising:
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a porous microprojection member having a wall that includes interior and exterior surfaces, said exterior surface substantially enclosing said interior surface; and
a biocompatible coating disposed on said interior surface, said microprojection member being adapted to substantially restrict contact of said coating with the biological tissue during insertion of said microprojection member into the tissue, said microprojection member having sufficient porosity to allow migration of the interstitial fluid through said wall of said microprojection member. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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Specification