Branch vessel stent and graft

• US 20050033406A1
• Filed: 07/15/2004
• Published: 02/10/2005
• Est. Priority Date: 07/15/2003
• Status: Abandoned Application

• Current Assignee: University of Iowa Research Foundation
• Original Assignee: University of Iowa Research Foundation
• Inventors: Hoballah, Jamal J., Barnhart, William H.
• Application Number:
  US10/891,917
• Publication Number:
  US 20050033406A1
• Time in Patent Office: Days
• US Class Current: 623/1.130
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0025 Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

Endovascular stents and grafts for repairing portions of anatomical vessels are provided. The stent grafts may be attached to a graft positionable at a junction where a vessel divides or branches with at least one other vessel for repair of an aneurysm in the region of the junction.

Claims

1. A frame for an anatomical vessel with an inner surface defining an inner circumference and at least one connecting branch vessel with an inner surface defining an inner circumference, comprising:

a first open-cylinder member with an outer surface defining a circumferential arc length, first and second opposing end portions, and a connection location, wherein

said circumferential arc length is at most equal to the anatomical vessel inner circumference, wherein

said first open-cylinder member is adapted for placement within the lumen of the anatomical vessel with a substantial portion of said first open-cylinder member outer surface contacting the anatomical vessel inner surface, wherein

said connection location is nearer to said first opposing end than said second opposing end; and

a first cylindrical connecting member connected to said first open-cylinder member at said connection location, said first cylindrical connecting member adapted for placement within the lumen of the first connecting branch vessel with a substantial portion of said first cylindrical connecting member outer surface contacting at least one branch vessel inner surface.

2. The frame of claim 1, wherein said first open-cylinder member is adapted to exert pressure on the anatomical vessel inner surface and said first cylindrical connecting member is adapted to exert pressure on the first connecting branch vessel inner surface, wherein the exerted pressures act to center said first open-cylinder member and said first cylindrical connecting member in the junction between the anatomical vessel and the at least one connecting branch vessel.

3. The frame of claim 1, wherein

said first open-cylinder member further comprises at least one aperture through said first open-cylinder member outer surface;

said first cylindrical connecting member further comprises at least one aperture through said first cylindrical connecting member outer surface; and

further comprising a fluid-tight sheath covering at least one of said apertures in said first open-cylinder member and said first cylindrical connecting member.

4. The frame of claim 1, further comprising:

a second open-cylinder member with an outer surface defining a circumferential arc length, first and second opposing end portions, and a connection location, wherein

said circumferential arc length is at most equal to the anatomical vessel inner circumference, wherein

said second open-cylinder member is adapted for placement within the lumen of the anatomical vessel with a substantial portion of said second open-cylinder member outer surface contacting the anatomical vessel inner surface, wherein

said second open-cylinder member contacts said first open-cylinder member to form at least one closed-cylinder region, wherein

said connection location is nearer to said first opposing end than said second opposing end; and

a second cylindrical connecting member connected to said second open-cylinder member at said connection location, said second cylindrical connecting member adapted for placement within the lumen of a second connecting branch vessel with a substantial portion of said second cylindrical connecting member outer surface contacting the second connecting branch vessel inner surface.

5. The frame of claim 4, wherein

said second open-cylinder member further comprises at least one aperture through said second open-cylinder member outer surface;

said second cylindrical connecting member further comprises at least one aperture through said second cylindrical connecting member outer surface; and

further comprising a fluid-tight sheath covering at least one of said apertures in said second open-cylinder member and said second cylindrical connecting member.

6. The frame of claim 5, wherein said first open-cylinder member and said second open-cylinder member are adapted to connect to a separate stent graft with a fluid-tight seal.

7. A stent for the anatomical vessels surrounding a junction between a first anatomical vessel and at least a second anatomical vessel, comprising:

a first open-cylinder stent portion with an outer surface, wherein said first open-cylinder stent portion is adapted for placement within the lumen of the first anatomical vessel with said outer surface substantially contiguous with the first anatomical vessel inner surface.

8. The stent of claim 7, wherein said first open-cylinder stent portion defines a first arc length, wherein said first arc length is less than the circumference of the first anatomical vessel inner surface.

9. The stent of claim 7, further comprising a fluid-tight cover, wherein said first open-cylinder stent portion defines a plurality of apertures, and said fluid-tight cover spans at least one said apertures.

10. The stent of claim 7, wherein a portion of said first open-cylinder stent portion allows bodily fluid to flow through said stent portion.

11. The stent of claim 7, wherein said first open-cylinder outer surface is convex when outside the lumen of the first anatomical vessel.

12. The stent of claim 7, further comprising:

a first lateral cylindrical member with an outer surface, said first lateral cylindrical member connected to said first open-cylinder stent portion, wherein said first lateral cylindrical member is adapted for placement within a lumen of the second anatomical vessel with said first lateral cylindrical member outer surface substantially contiguous with the first anatomical vessel inner surface.

13. The stent of claim 12, wherein said first lateral cylindrical member is an open-cylinder.

14. The stent of claim 12, wherein said first open-cylinder stent portion and said first lateral cylindrical member are comprised of a form-returning material.

15. The stent of claim 14, wherein said first open-cylinder stent portion and said first lateral cylindrical member are comprised of a shape memory alloy.

16. The stent of claim 12, wherein said first lateral cylindrical member defines a longitudinal axis along the length of said first lateral cylindrical member, wherein said first lateral cylindrical member is movable relative to said first open-cylinder stent portion such that said longitudinal axis remains substantially within a eighty degree (80°

) cone, wherein said cone is stationary in relation to said first open-cylinder stent portion with the cone vertex oriented toward the outer surface of said first open-cylinder stent portion.

17. The stent of claim 16, wherein said cone defines a main axis, wherein said cone main axis is perpendicular to said first open-cylinder stent portion outer surface at the point where said main axis intersects said first open-cylinder stent portion outer surface.

18. The stent of claim 12, wherein said first open-cylinder stent portion and said first lateral cylindrical member are adapted to be collapsed for delivery with a body introduction device.

19. The stent of claim 12, wherein said first open-cylinder stent portion is adapted to exert pressure on the first anatomical vessel inner surface and said first lateral cylindrical member is adapted to exert pressure on the second anatomical vessel inner surface, wherein the exerted pressures act to center said first open-cylinder stent portion and said first lateral cylindrical member in the junction between the first and second anatomical vessels.

20. The stent of claim 12, further comprising:

a second open-cylinder stent portion with at least one aperture and an outer surface, wherein said second open-cylinder stent portion is adapted for placement within the lumen of the first anatomical vessel with said outer surface substantially contiguous with the first anatomical vessel inner surface and in overlapping relation with said first open-cylinder stent portion; and

a second lateral cylindrical member with at least one aperture and an outer surface, said second lateral cylindrical member connected to said second open-cylinder stent portion, wherein said second lateral cylindrical member is adapted for placement within the lumen of a third anatomical vessel with said second lateral cylindrical member outer surface substantially contiguous with the third anatomical vessel inner surface.

21. The stent of claim 20, further comprising:

a fluid-tight cover spanning at least one said aperture in at least one of said second open-cylinder stent portion and said second lateral cylindrical member.

22. The stent of claim 20, wherein said first open-cylinder stent portion defines a first arc length and said second open-cylinder stent portion defines a second arc length, and wherein the sum of said first and second arc lengths is at least equal to the inner circumference of the first anatomical vessel.

23. The stent of claim 20, wherein said second lateral cylindrical member is an open-cylinder.

24. The stent of claim 20, wherein said first and second open-cylinder stent portions and said first and second lateral cylindrical members are comprised of a form-returning material.

25. The stent of claim 24, wherein said first and second open-cylinder stent portions and said first and second lateral cylindrical members are comprised of a shape memory alloy.

26. The stent of claim 20, further comprising:

a third open-cylinder stent portion with at least one aperture and an outer surface, wherein said third open-cylinder stent portion is adapted for placement within the lumen of the first anatomical vessel with said outer surface substantially contiguous with the first anatomical vessel inner surface and in overlapping relation with at least one of the first and second open-cylinder stent portions;

a third lateral cylindrical member with at least one aperture and an outer surface, said third lateral cylindrical member connected to said third open-cylinder stent portion, wherein said third lateral cylindrical member is adapted for placement within the lumen of a fourth anatomical vessel with said third lateral cylindrical member outer surface substantially contiguous with the fourth anatomical vessel inner surface.

27. A method for grafting a region between a reference blood vessel and at least one branching blood vessel, comprising:

collapsing a first open-cylinder stent portion adapted for placement within the lumen of the reference blood vessel;

placing the collapsed first open-cylinder stent portion within the lumen of at least one of the reference blood vessel and a first branching blood vessel; and

expanding the first open-cylinder stent portion, wherein said expanding results in a substantial portion of the first open-cylinder stent portion contacting the reference blood vessel inner surface.

28. The method of claim 27, further comprising:

collapsing a first lateral stent portion attached to the first open-cylinder stent portion, the first lateral stent portion adapted for placement within the lumen of the first branching blood vessel, and wherein the first lateral stent portion is cylindrical;

placing the collapsed first later stent portion within the lumen of at least one of the reference and first branching blood vessels; and

expanding the first lateral stent portion, wherein said expanding result in a substantial portion of the first lateral stent portion contacting the first branching blood vessel inner surface.

29. The method of claim 28 further comprising:

self-aligning the first open-cylinder stent portion with the lumen of the reference blood vessel and the first lateral stent portion within the lumen of the first branching blood vessel, said self-aligning performed by at least one of the first open-cylinder stent portion exerting force on the reference blood vessel inner surface and the first lateral stent portion exerting force on the first branching blood vessel inner surface.

30. The method of claim 28, further comprising:

collapsing a second open-cylinder stent portion and a second lateral stent portion attached to the second open-cylinder stent portion, the second open-cylinder stent portion adapted for placement within the lumen of the reference blood vessel, the second lateral stent portion adapted for placement within the lumen of a second branching blood vessel, and wherein the second lateral stent portion is cylindrical;

placing the collapsed second open-cylinder stent portion and collapsed second lateral stent portion within the lumen of at least one of the reference, first branching and second branching blood vessels; and

expanding the second open-cylinder stent portion and the second lateral stent portion, wherein said expanding results in a substantial portion of the second open-cylinder stent portion contacting the reference blood vessel inner surface, the second open-cylinder stent portion overlapping the first open-cylinder stent portion, and a substantial portion of the second lateral stent portion contacting the second branching blood vessel inner surface.

31. The method of claim 30, wherein said expanding the collapsed second open-cylinder stent portion results in the first and second open-cylinder stent portions together contacting at least one circumferential ring of the reference blood vessel.

32. The method of claim 30 further comprising:

self-aligning the second open-cylinder stent portion with the lumen of the reference blood vessel and the second lateral stent portion within the lumen of the second branching blood vessel, said self-aligning performed by at least one of the second open-cylinder stent portion exerting force on the reference blood vessel inner surface and the second lateral stent portion exerting force on the second branching blood vessel inner surface.

33. The method of claim 30, further comprising:

collapsing a third open-cylinder stent portion and a third lateral stent portion attached to the third open-cylinder stent portion, the third open-cylinder stent portion adapted for placement within the lumen of the reference blood vessel, the third lateral stent portion adapted for placement within the lumen of a third branching blood vessel, and wherein the third lateral stent portion is cylindrical;

placing the collapsed third open-cylinder stent portion and collapsed third lateral stent portion within the lumen of at least one of the reference, first branching, second branching, or third branching blood vessel; and

expanding the third open-cylinder stent portion and the third lateral stent portion, wherein said expanding results in a substantial portion of the third open-cylinder stent portion contacting the reference blood vessel inner surface, the third open-cylinder stent portion overlapping the first and second open-cylinder stent portions, and a substantial portion of the third lateral stent portion contacting the third branching blood vessel inner surface.

34. The method of claim 33, wherein said expanding the collapsed third open-cylinder stent portion results in the first, second and third open-cylinder stent portions together contacting at least one circumferential ring of the reference blood vessel.

35. The method of claim 33 further comprising:

self-aligning the third open-cylinder stent portion with the lumen of the reference blood vessel and the third lateral stent portion within the lumen of the third branching blood vessel, said self-aligning performed by at least one of the third open-cylinder stent portion exerting force on the reference blood vessel inner surface and the third lateral stent portion exerting force on the third branching blood vessel inner surface.