Devices for analyte concentration determination and methods of manufacturing and using the same
First Claim
1. A test strip for determining the concentration of at least one analyte in a physiological sample, said test strip comprising a fluid transfer element for transferring said sample to a reaction area of said test strip, said fluid transfer element comprising at least a first area and a second area, wherein the thickness of said first area differs from the thickness of said second area.
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Accused Products
Abstract
Test strips for determining the concentration of at least one analyte, e.g., glucose, in a physiological sample and methods for their manufacture and use and are provided. The subject test strips include a transfer element for facilitating the transfer of sample to a reaction area of the test strip. In certain embodiments, the transfer element, typically porous, has a first area and a second area, and in certain embodiments the two areas have different thicknesses. In other embodiments, the transfer element is non-porous and is configured to transfer sample by wicking it between the transfer element and the reaction area of the test strip. In the subject methods, the transport element facilitates transfers of a sample to a reaction area of the test strip. The subject test strips and methods find use in a variety of different applications, particularly in the determination of glucose concentrations.
24 Citations
63 Claims
- 1. A test strip for determining the concentration of at least one analyte in a physiological sample, said test strip comprising a fluid transfer element for transferring said sample to a reaction area of said test strip, said fluid transfer element comprising at least a first area and a second area, wherein the thickness of said first area differs from the thickness of said second area.
- 17. A test strip for determining the concentration of at least one analyte in a physiological sample, said test strip comprising a fluid transfer element for transferring said sample to a reaction area of said test strip, said fluid transfer element comprising at least a first area and a second area, wherein said second section is configured to receive sample and said first section is configured to receive excess sample.
- 30. A test strip for determining the concentration of at least one analyte in a physiological sample, said test strip comprising a non-porous transport element for transferring said sample to a reaction area of said test strip.
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49. A method for making a transport element of a test strip, said method comprising:
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(a) providing a compression mold assembly configured to make a transport element having at least a first area and a second area, wherein the thickness of said first area and said second area differ;
(b) inserting a precursor material within said mold assembly; and
(c) applying pressure to said precursor material to provide said transport element having at least a first area and a second area, wherein the thickness of said first area and said second area differ.
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- 50. A method for determining the concentration of at least one analyte in a physiological sample, said method comprising applying sample to a test strip comprised of a fluid transport element, wherein said fluid transport element is comprised of at least a first area and a second area having different thicknesses.
- 55. A method for determining the concentration of at least one analyte in a physiological sample, said method comprising applying sample to one or more sides of a test strip.
Specification