Solid oral anti-tartar and anti-plaque compositions

• US 20050042184A1
• Filed: 11/05/2002
• Published: 02/24/2005
• Est. Priority Date: 11/06/2001
• Status: Abandoned Application

• Current Assignee: Perfetti Van Melle S.P.A.
• Original Assignee: Perfetti Van Melle S.P.A.
• Inventors: Barrica, Andrea, Salmoiraghi, Guglielmo, Colle, Roberto
• Application Number:
  US10/494,570
• Publication Number:
  US 20050042184A1
• Time in Patent Office: Days
• US Class Current: 424/52
• CPC Class Codes: A23G 3/368 containing vitamins, antibiotics
• CPC Class Codes: A23G 4/126 containing vitamins, antibiotics
• CPC Class Codes: A61K 8/21 Fluorides; Derivatives thereof
• CPC Class Codes: A61K 8/24 Phosphorous; Compounds thereof
• CPC Class Codes: A61K 8/25 Silicon; Compounds thereof
• CPC Class Codes: A61K 8/29 Titanium; Compounds thereof
• CPC Class Codes: A61K 8/345 containing more than one hydroxy group
• CPC Class Codes: A61K 8/736 Chitin; Chitosan; Derivatives thereof
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

Oral formulations in the form of chewing gum comprising: a. polyphosphates; b. hydrated silica; c. a source of fluoride ions; d. a polymer derived from chitin, or other naturally occurring hydrocolloids or a mixture thereof; e. optionally extracts or active ingredients of vegetable origin and/or antibacterial/disinfectant agents. The compositions of the invention are useful as adjuvants in dental hygiene, in particular to reduce tartar deposits

Claims

1. Oral formulations in solid form, comprising:

a. polyphosphates;

b. an abrasive agent;

c. a source of fluoride ions;

d. a polymer derived from chitin, or other naturally occurring hydrocolloids or a mixture thereof;

e. optionally extracts or active ingredients of vegetable origin;

f. optionally antibacterial/disinfectant agents.

2. Formulations as claimed in claim 1, wherein the polyphosphates are selected from tripolyphosphates, pyrophosphates or mixtures thereof.

3. Formulations as claimed in claim 2, comprising a mixture of alkali metal pyrophosphates and tripolyphosphates.

4. Formulations as claimed in claim 1, further containing excipients selected from gum base, sweeteners, polyalcohols, flavourings, dyes, softeners, plasticisers, stabilisers and thickeners.

5. Formulations as claimed in claim 1, wherein the abrasive agent is hydrated silica, calcium carbonate and talc, either individually or in a mixture thereof.

6. Formulations as claimed in claim 1, wherein the chitin-derived polymer is a (partly or totally) deacetylated derivative of chitin, optionally chemically modified, optionally in association with other polysaccharides hydrocolloids.

7. Formulations as claimed in claim 6, wherein the polymer is a chitosan.

8. Formulations as claimed in claim 7, wherein the chitosan is chitosan oligosaccharide.

9. Formulations as claimed in claim 1, wherein the naturally occurring hydrocolloids are xanthan gum, locust bean gum, alginates, carrageeneens, gellan gum or other polysaccharides with bioadhesive properties.

10. Formulations as claimed in claim 1 containing extracts with anti-inflammatory, wound-healing, antihemorrhagic, soothing, emollient, decongestant and antiseptic properties.

11. Formulations as claimed in claim 10, wherein the vegetable extracts are selected from extracts of Centella asiatica, Malva sylvestris, Melaleuca alternifolia, Commiphora abyssinica (myrrh), Krameria triandra (rhatany), Acacia catechu, Medicago sativa (alfalfa), resins of the genus Styrax, such as Styrax benzoin (benzoin), Matricaria recutita (camomile), Echinacea purpura (echinacea) and Croton lechleri (dragon'"'"'s blood).

12. Formulations as claimed in claim 1, containing 0.5 to 5% by weight of polyphosphates, 0.5 to 7% by weight of an abrasive agent (possibly wholly or partly encapsulated), 0.5 to 5% by weight of a polymer derived from chitin, and a source of fluoride ions able to guarantee a fluoride intake of 0.005 to 0.2%.

13. Formulations as claimed in claim 12, further containing 0.01 to 2% by weight of vegetable extracts.

14. Formulations as claimed in claim 1, comprising disinfectant and/or antibacterial agents selected from triclosan, zinc oxide and zinc salts, either alone or in combination with one another, in concentrations of between 0.1% and 5%.

15. Formulations as claimed in claim 1, wherein said formulations are chewing gum or candies.