Systems for capture and analysis of biological particles and methods using the systems
First Claim
Patent Images
1. A method for capturing biological particles, comprising:
- contacting a capture system with biological particles under conditions whereby the biological particles bind to the capture system, wherein;
the capture system comprises a plurality of addressed loci;
the capture system comprises an addressed collection of polypeptide-tagged molecules bound to addressed capture agents at each locus;
the capture agents at each locus bind to the same polypeptide tag;
the polypeptide tag to which the capture agent binds is different among the loci; and
each locus in capture system contains a plurality of different molecules each with the same tag bound to the capture agents at the locus.
3 Assignments
0 Petitions
Accused Products
Abstract
Cell based methods designed to assess intracellular and extracellular activities and interactions and to identify compounds and conditions that modulate such activities and interactions are provided. The cell based methods employ capture systems that display collections of tagged molecules specifically linked to capture agents.
149 Citations
79 Claims
-
1. A method for capturing biological particles, comprising:
-
contacting a capture system with biological particles under conditions whereby the biological particles bind to the capture system, wherein;
the capture system comprises a plurality of addressed loci;
the capture system comprises an addressed collection of polypeptide-tagged molecules bound to addressed capture agents at each locus;
the capture agents at each locus bind to the same polypeptide tag;
the polypeptide tag to which the capture agent binds is different among the loci; and
each locus in capture system contains a plurality of different molecules each with the same tag bound to the capture agents at the locus. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79)
-
Specification