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Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure

  • US 20050043675A1
  • Filed: 08/21/2003
  • Published: 02/24/2005
  • Est. Priority Date: 08/21/2003
  • Status: Active Grant
First Claim
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1. A system, comprising:

  • a transdermal drug delivery device;

    an implantable cardiac rhythm management (CRM) device communicatively coupled to the transdermal drug delivery device, the implantable CRM device including;

    an ischemia detector producing an ischemia indicating signal;

    a drug level detector producing an indication of a blood drug concentration; and

    a drug delivery controller coupled to the ischemia detector and the drug level indicator; and

    an external device communicatively coupled to the implantable CRM device, the external device including an external user input receiving an external user command, wherein the drug delivery controller controls the transdermal drug delivery device based on at least one of the ischemia indicating signal, the indication of the blood drug concentration, and the external user command.

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