System and method of assessment of the efficacy of treatment of neurological disorders using the electroencephalogram
First Claim
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1. A system for assessing the efficacy of treatment of a neurological disorder comprising:
- at least two electrodes for acquiring electrophysiological signals from the body;
a processor for calculating from said electrophysiological signals at least one feature relating to the efficacy of said treatment.
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Abstract
Disclosed is a system and method of assessing the efficacy of treatment of neurological or psychological disorders. The preferred embodiment uses at least two surface electrodes to acquire EEG signals from the surface of a patient'"'"'s body, a processor for computing from the EEG signals various features and indices that are representative of the patient'"'"'s neurological or psychological state. Changes in these parameters may be used to assess the efficacy of treatment and to modify the treatment to optimize the resultant patient state.
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Citations
38 Claims
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1. A system for assessing the efficacy of treatment of a neurological disorder comprising:
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at least two electrodes for acquiring electrophysiological signals from the body;
a processor for calculating from said electrophysiological signals at least one feature relating to the efficacy of said treatment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A system for assessing the efficacy of treatment of a neurological disorder comprising:
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at least two electrodes for acquiring electrophysiological signals from a body;
data acquisition circuitry for acquiring from said electrodes a first electrophysiological signal representing a baseline condition and a second electrophysiological signal representing a subsequent condition;
a processor for calculating from said electrophysiological signals received from the data acquisition circuitry;
(a) at least one feature relating to the patient state during the baseline condition;
(b) at least one feature relating to the patient state during the subsequent condition; and
(c) the difference between said features relating to the baseline and subsequent conditions, such that said difference relates to the efficacy of said treatment.
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19. A system for optimizing the efficacy of treatment of a neurological disorder comprising:
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at least two electrodes for acquiring electrophysiological signals from a body;
processor for calculating from said electrophysiological signals at least one feature relating to the efficacy of said treatment;
data acquisition circuitry for acquiring said electrophysiological signals from said electrodes and converting said electrophysiological signals to a form usable by said processor;
a processor for varying the treatment parameters of a neurostimulator in order to maximize the calculated treatment efficacy.
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20. A method of assessing the efficacy of treatment of a neurological disorder comprising the steps of:
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acquiring electrophysiological signals from a body through electrodes placed on the body;
calculating from said electrophysiological signals at least one feature relating to the efficacy of said treatment. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A method of assessing the efficacy of treatment of a neurological disorder comprising:
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positioning a least two electrodes on a body being treated;
acquiring a first electrophysiological signal from the body at a baseline condition;
acquiring a second electrophysiological signal from the body during a subsequent condition;
calculating at least one feature relating to the patient state during the baseline condition;
calculating at least one feature relating to the patient state during the subsequent condition;
calculating at the difference between the features calculated during the baseline and subsequent conditions, such that the difference relates to the efficacy of said treatment.
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38. A method of optimizing the efficacy of treatment of a neurological disorder comprising:
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positioning at least two electrodes on a body being treated;
acquiring electrophysiological signals from the body;
calculating at least one feature relating to the efficacy of said treatment;
varying treatment parameters in order to maximize the calculated treatment efficacy.
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Specification