Device for holding a substance library carrier
First Claim
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1. A device for holding a substance library carrier, comprising two holding elements that are fixable with each other, and that form a layer composite comprising:
- (i) a lid element having a detection surface with a substance library on its underneath side and being optically translucent at least in an area of the detection surface, (ii) a sealing intermediate element having an enclosed recess; and
(iii) a base element being optically translucent at least in an area of the detection surface of the lid element, wherein the lid element, the intermediate element and the base element together form an optically translucent chamber having a chamber space.
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Abstract
Disclosed are devices for holding a substance library carrier, and which are useful in conducting reactions in which binding between complementary molecules is measured qualitatively or quantitatively. Also disclosed are methods for conducting such reactions in the device.
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Citations
45 Claims
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1. A device for holding a substance library carrier, comprising two holding elements that are fixable with each other, and that form a layer composite comprising:
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(i) a lid element having a detection surface with a substance library on its underneath side and being optically translucent at least in an area of the detection surface, (ii) a sealing intermediate element having an enclosed recess; and
(iii) a base element being optically translucent at least in an area of the detection surface of the lid element, wherein the lid element, the intermediate element and the base element together form an optically translucent chamber having a chamber space. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43)
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44. A first device for filling a second device for holding a substance library carrier, wherein the second device comprises two holding elements that are fixable with each other, and that form a layer composite comprising:
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(i) a lid element having a detection surface with a substance library on its underneath side and being optically translucent at least in an area of the detection surface, (ii) a sealing intermediate element having an enclosed recess; and
(iii) a base element being optically translucent at least in an area of the detection surface of the lid element, wherein the lid element, the intermediate element and the base element together form an optically translucent sample chamber having a chamber space, and wherein the first device comprises a body and a cover fixable to the body, wherein the body contains recesses for a filling unit, a ventilation unit and the second device, and wherein the recesses are arranged such that the sample chamber of the second device may be loaded and vented through puncturing of the intermediate element from its side. - View Dependent Claims (45)
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Specification