Steady state free precession based magnetic resonance thermometry
First Claim
1. A computer readable medium encoded with a program for performing Magnetic Resonance based thermometry, the program comprising the steps of:
- transmitting a first RF pulse sequence;
receiving a first set of MR signal data, the first set of MR signal data corresponding to the first RF pulse sequence;
receiving a second set of MR signal data;
determining a phase difference between a peak of the first set of MR signal data and a peak of the second set of MR signal data; and
converting the phase difference to a change in temperature.
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Abstract
Disclosed is a method and system for steady state free precession based magnetic resonance thermometry that measures changes in temperature on a pixel by pixel basis. The method comprises generating an RF pulse sequence used to find the proton resonance frequency shift, which is proportional to temperature change, processing the resultant MRI data to measure the proton frequency shift, and converting the measured proton frequency shift into change in temperature data. Further disclosed is a method for identifying and compensating for temperature drifts due to core heating of the gradient magnet.
16 Citations
27 Claims
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1. A computer readable medium encoded with a program for performing Magnetic Resonance based thermometry, the program comprising the steps of:
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transmitting a first RF pulse sequence;
receiving a first set of MR signal data, the first set of MR signal data corresponding to the first RF pulse sequence;
receiving a second set of MR signal data;
determining a phase difference between a peak of the first set of MR signal data and a peak of the second set of MR signal data; and
converting the phase difference to a change in temperature. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method for performing Magnetic Resonance based thermometry comprising the steps of:
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generating a first RF pulse sequence;
receiving a first set of MR signal data, the first set of MR signal data corresponding to the first RF pulse sequence;
determining a first phase corresponding to a peak within the first set of MR signal data;
storing the first phase;
receiving a second set of MR signal data;
determining a second phase corresponding to a peak within the second set of MR data;
computing a phase difference between the first phase and the second phase; and
converting the phase difference to a change in temperature data. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27)
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24. A system for performing MRI-based thermometry, comprising:
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a gradient magnet;
an RF coil;
an RF amplifier connected to the RF coil;
a spectrometer; and
a computer connected to the RF amplifier, the RF coil, and the gradient magnet, the computer having a computer readable medium encoded with a program for performing steady state free precession based thermometry, wherein the program is for generating an RF pulse sequence used to find the proton frequency shift, processing the resultant MRI data to measure the proton frequency shift, and converting the measured proton frequency shift into change in temperature data.
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Specification