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Molecular detection and assay by electrobiochip micro-array

  • US 20050053996A1
  • Filed: 10/18/2004
  • Published: 03/10/2005
  • Est. Priority Date: 11/29/2001
  • Status: Active Grant
First Claim
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1. A method of detecting trace quantities of a molecular target by exploiting a specific interaction between the target and two molecular probes, comprising:

  • attaching one of said molecular probes to an electrically conductive magnetic bead, fixing the other of said probes in a gap between two electrodes, applying a perpendicular magnetic field to the base of the gap, applying an electric potential to said electrodes, and monitoring for an increase in electrical current from one of the electrodes to the other as might occur if said conductive bead is drawn into said gap by said specific interaction and fixed between the electrodes by said magnetic field.

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