Novel human semaphorin homologs and polynucleotides encoding the same

• US 20050054040A1
• Filed: 04/28/2004
• Published: 03/10/2005
• Est. Priority Date: 05/18/2000
• Status: Active Grant

• Current Assignee: John Scoville, Turner C. Alexander Jr, Walke D. Wade, Xiaoming Wang
• Original Assignee: John Scoville, Turner C. Alexander Jr, Walke D. Wade, Xiaoming Wang
• Inventors: Wang, Xiaoming, Scoville, John, Walke, D. Wade, Turner, C. Alexander Jr.
• Granted Patent: US 7,199,221 B2
• Time in Patent Office: Days
• US Class Current: 435/69.100
• CPC Class Codes: C07K 14/4703 Inhibitors; Suppressors

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising at a nucleotide sequence encoding an amino acid sequence drawn from the group consisting of SEQ ID NOS:

2, 4, 6, 8, 10, 12, 14, 16, 19, 21, 23, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, and 49.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

4; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

3 or the complement thereof.

3. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

4.

4. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

2.

5. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

12.

6. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

29; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

28 or the complement thereof.

7. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

29.

8. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

33.

9. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

25.