Penile reconstruction
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Accused Products
Abstract
A cartilaginous structural member (CSM) for use in penile reconstruction, for the correction of developmental defects, postoperative reconstruction, and for reconstructive preprosthetic surgery. The cartilaginous structural member (CSM) comprise of live cells seeded onto pre-formed shaped structure which may be biodegradable. The live cells may comprise chondrocyte and the cartilaginous structural member (CSM) for use in reconstructive surgery may be constructed of polyglycolic acid. The implant structure is applicable to use for the regeneration and reconstruction or augmentation of semirigid members of the body such as the penis, nose, ear and locations which naturally has cartilage. Further, the cartilaginous structural member (CSM) may be used in plastic surgery such as, for example, breast augmentation or pectoral augmentation. The cartilaginous structural member (CSM) may be a composite cartilaginous structural member (CSM) comprising additional anchoring and strengthening elements for anchoring or changing the structural strength of said composite cartilaginous structural member (CSM).
25 Citations
46 Claims
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1-31. -31. (cancelled)
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32. A method for treating a patient having an anatomical defect not caused by absent, damaged or diseased cartilage and which can be treated, at least in part, by providing structural support to adjacent tissue comprising the steps of:
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a) providing a polymeric matrix shaped in the form of the desired support member;
b) depositing dissociated cartilage forming cells on and in said matrix to form a matrix/cell construct; and
c) implanting said matrix/cell construct in said patient at a site needing structural support, wherein said construct forms a cartilaginous structural member having controlled biomechanical properties providing the required structural support in the area of said defect. - View Dependent Claims (33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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Specification