Spatial detectors for in-vivo measurement of bio chemistry
First Claim
1. ) Apparatus for in-vivo determination of bio chemical concentrations comprising an optical illumination source and a detector, said detector characterized as including at least one pressure transducer having a geometric shape which results in a point within a test tissue being more strongly coupled than immediately surrounding points.
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Abstract
Acoustic detectors having special arrangements and shapes which favor receipt of energy from a particular direction are presented for use in bio chemical concentration measurement. These detectors may include those which aim to receive acoustic energy from a portion of tissue lying slightly below the surface where interstitial fluid containing glucose and glucose indicators may be probed with middle infrared electromagnetic radiation. These devices may be arranged to listen not only to a particular direction in the tissue, but additionally to a particular chosen point. In some versions, acoustic detectors are formed of concentric ring elements having geometries which facility constructive interference between successive wave fronts of a received acoustic wave. Alternatively, spherically shaped reflecting surfaces may be used as a lens to couple the energy emitted from interstitial fluid to a transducer which lies at or near the skin surface.
18 Citations
18 Claims
- 1. ) Apparatus for in-vivo determination of bio chemical concentrations comprising an optical illumination source and a detector, said detector characterized as including at least one pressure transducer having a geometric shape which results in a point within a test tissue being more strongly coupled than immediately surrounding points.
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13. ) Methods of in-vivo determination of a bio chemical concentration by photoacoustic spectroscopy comprising the steps:
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illuminating a tissue sample with middle infrared light;
receiving pressure waves emanating from illuminated tissue at a skin surface interface;
converting those pressure waves into electronic signals at a detector shaped such that energy emitted from a particular point is coupled to the transducer with a greater efficiency than other nearby points. - View Dependent Claims (14, 15, 18)
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- 16. ) Methods of 14, said converting pressure waves is done at a plurality of areas distributed about a symmetry axis.
Specification