Highly portable and wearable blood analyte measurement system

• US 20050054907A1
• Filed: 09/08/2003
• Published: 03/10/2005
• Est. Priority Date: 09/08/2003
• Status: Abandoned Application

• Current Assignee: James Plante, Joseph Page
• Original Assignee: James Plante, Joseph Page
• Inventors: Page, Joseph, Plante, James
• Application Number:
  US10/656,376
• Publication Number:
  US 20050054907A1
• Time in Patent Office: Days
• US Class Current: 600/316
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/681 Wristwatch-type devices

Abstract

Non-invasive wearable systems for continuous measurement of blood glucose concentrations help diabetics maintain best awareness and control. A wearable article such as a wristwatch includes elements integrated therewith to provide for biometric measurements. Specifically, both optical and acoustic transducers are arranged within an article such that they are coupled to tissue in a manner which permits blood analytes measurements to be made. In best versions, a quantum cascade laser is arranged with crystalline acoustic detectors in a photoacoustic effect measurement scheme. Laser pulses stimulate special vibrational states of glucose molecules to produce an acoustic return signal to be received at a piezoelectric detector. A wristwatch case may include a back member which supports arrangements and coupling between the back of the watch, elements contained therein, and tissue in contact with the device.

Claims

1. ) Portable, non-invasive systems for blood analyte measurement integrated with a common article wearable about the body comprising:

a rigid case operable for containing;

a processing unit in communication with;

an optical source; and

an acoustic detector,

said rigid case having a top side and a bottom side, the bottom side suitable for supporting said acoustic detector and said optical source whereby they may be coupled to human tissue.

2. ) Apparatus of claim 1, said rigid case forming an enclosed space of between one and ten cubic centimeters such that the article may be easily worn about the body.

3. ) Apparatus of claim 2, said elements being integrated together with timekeeping facility to form a wrist watch type article suitable for wear at the wrist.

4. ) Apparatus of claim 3, said elements are arranged to effect a photoacoustic effect measurement of blood analytes via optical stimulation of pressure waves in an elastic tissue medium.

5. ) Apparatus of claim 3, said optical source is comprised of at least one quantum cascade semiconductor laser operable for producing beams of light in a Mid-IR spectra between 2-200 microns.

6. ) Apparatus of claim 5, said beam of light is comprised of a plurality of center wavelengths at least one tuned to natural resonances of a glucose molecule.

7. ) Apparatus of claim 3, said acoustic detector is characterized as an audio microphone.

8. ) Apparatus of claim 7, said acoustic detector is at least one PZT crystal operable for producing an electrical output in response to incident pressure.

9. ) Apparatus of claim 8, said acoustic detector includes an array of discrete elements tuned to a particular region.

10. ) Apparatus of claim 3, said rigid case bottom side supports an optical and acoustic coupling to tissue and may be fastened to the human wrist whereby the bottom side makes intimate contact with tissue at the top of the wearer'"'"'s wrist.

11. ) Apparatus of claim 10, back of watch case provides optical coupling to tissue whereby light penetrates the tissue up to about 100 microns in depth.

12. ) Apparatus of claim 10, back of watch case provides acoustic coupling to tissue whereby acoustic energy originating in tissue below the skin surface is coupled into the case via said acoustic detector.

13. ) Apparatus of claim 10, said case further comprises a user interface operable for presenting indicia at a display means.

14. ) Apparatus of claim 10, said case further comprises a data output port whereby information contained in a memory may be electronically passed to external systems including a computer.