Biochip devices for ion transport measurement, methods of manufacture, and methods of use
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Accused Products
Abstract
The present invention provides biochips for ion transport measurement, ion transport measuring devices that comprise biochips, and methods of using ion transport measuring devices and biochips that allow for the direct analysis of ion transport functions or properties. The present invention provides biochips, devices, apparatuses, and methods that allow for automated detection of ion transport functions or properties. The present invention also provides methods of making biochips and devices for ion transport measurement that reduce the cost and increase the efficiency of manufacture, as well as improve the performance of the biochips and devices. These biochips and devices are particularly appropriate for automating the detection of ion transport functions or properties, particularly for screening purposes.
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Citations
197 Claims
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1-164. -164. (canceled)
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165. A device for ion transport measurement, comprising:
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an upper chamber piece that comprises at least one well, wherein said at least one well is open at its upper and lower ends; and
a chip that comprises at least one ion transport measuring means, wherein said chip has been treated to enhance the electrical sealing properties of said at least one ion transport measuring means;
wherein said chip is attached to the bottom of said upper chamber piece such that each of said at least one ion transport measuring means is in register with one of said at least one well. - View Dependent Claims (166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197)
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Specification