Electroactive polymer actuated medication infusion pumps

• US 20050065500A1
• Filed: 11/04/2004
• Published: 03/24/2005
• Est. Priority Date: 10/02/2002
• Status: Abandoned Application

• Current Assignee: Lucien Alfred Jr. Couvillon, Michael S. Banik, Pete M. Nicholas
• Original Assignee: Lucien Alfred Jr. Couvillon, Michael S. Banik, Pete M. Nicholas
• Inventors: Nicholas, Pete M., Couvillon, Lucien Alfred Jr., Banik, Michael S.
• Application Number:
  US10/981,098
• Publication Number:
  US 20050065500A1
• Time in Patent Office: Days
• US Class Current: 604/891.100
• CPC Class Codes: A61M 2205/0283 Electro-active polymers [EAP]
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: F04B 43/0054 particularities of the flexible members
• CPC Class Codes: F04B 43/084 the tubular member being deformed by stretching or distortion
• CPC Class Codes: F04B 45/02 having bellows

Abstract

The present invention is directed to a drug delivery pump apparatus, which comprises: (a) an expandable and contractible enclosure having an interior volume that defines a medication reservoir; (b) one or more electroactive polymer actuators; (c) a medication outlet port providing fluid communication between the interior volume of the contractible and expandable enclosure and an exterior of the delivery pump apparatus; and (d) a control unit electrically coupled to the one or more actuators and sending control signals to the same. The one or more electroactive polymer actuators act to reduce the interior volume of the contractible and expandable enclosure based upon the received control signals. The present invention is also directed to a method of delivering a liquid therapeutic agent to a patient. The method comprises: (a) providing the above infusion pump apparatus; (b) placing the outlet port of the infusion pump apparatus in fluid communication with a patient; and (c) sending the control signals to the one or more actuators to reduce the internal volume of the contractible and expandable enclosure, thereby forcing a portion of the liquid therapeutic agent within the medication reservoir through the outlet port and into the patient.

Claims

1. A drug delivery pump apparatus comprising:

(a) a contractible and expandable enclosure having an interior volume defining a medication reservoir;

(b) an electroactive polymer actuator, said electroactive polymer actuator reducing said interior volume of said contractible and expandable enclosure upon contraction of said electroactive polymer actuator based upon received control signals;

(c) a medication outlet port providing fluid communication between said interior volume of said contractible and expandable enclosure and an exterior of said delivery pump apparatus; and

(d) a control unit electrically coupled to said actuator and sending said control signals to said actuator.

2. The drug delivery pump apparatus of claim 1, wherein said contractible and expandable enclosure comprises two or more electroactive polymer actuators.

3. The drug delivery pump apparatus of claim 1, further comprising a housing that encloses said contractible and expandable enclosure.

4. The drug delivery pump apparatus of claim 3, wherein said housing further encloses said control unit.

5. The drug delivery pump apparatus of claim 1, wherein said contractible and expandable enclosure comprises a bellows.

6. The drug delivery pump apparatus of claim 1, wherein said actuator comprises an electroactive polymer region, a counter-electrode region, and an electrolyte-containing region disposed between said electroactive polymer region and said counter-electrode region.

7. The drug delivery pump apparatus of claim 6, wherein said electroactive polymer comprises an electroactive polymer selected from polyaniline, polysulfone, and polyacetylene.

8. The drug delivery pump apparatus of claim 6, wherein said electroactive polymer comprises polypyrrole.

9. The drug delivery pump apparatus of claim 6, further comprising a conductive housing that encloses said contractible and expandable enclosure, wherein said housing serves as said counter-electrode or as a contact for said electroactive polymer.

10. The drug delivery pump apparatus of claim 6, wherein said contractible and expandable enclosure comprises a conductive bellows and wherein said bellows further serves as said counter-electrode or as a contact for said electroactive polymer.

11. The drug delivery pump apparatus of claim 1, wherein said contractible and expandable enclosure comprises an elastic wall.

12. The drug delivery pump apparatus of claim 1, wherein said actuator is disposed within or upon a wall of said contractible and expandable enclosure.

13. The drug delivery pump apparatus of claim 12, wherein said enclosure wall comprises an inner layer, an outer layer, a counter-electrode region, an electrolyte-containing region and a electroactive polymer region, and wherein said counter-electrode region, said electrolyte-containing region and said electroactive polymer region are disposed between said inner and outer layers.

14. The drug delivery pump apparatus of claim 1, wherein said medication outlet port is provided with a control valve that is operable based upon received control signals.

15. The drug delivery pump apparatus of claim 1, further comprising a wireless power transmission interface coupled to a rechargeable battery within said control unit.

16. The drug delivery pump apparatus of claim 1, further comprising a first wireless transceiver coupled to said control unit.

17. The drug delivery pump apparatus of claim 1, further comprising a sensor coupled to said control unit.

18. The drug delivery pump apparatus of claim 17, wherein said sensor is a strain gauge.

19. The drug delivery pump apparatus of claim 17, wherein said sensor is a chemical sensor that measures a detectable chemical species.

20. A method of delivering a liquid therapeutic agent to a patient comprising:

providing the infusion pump apparatus of claim 1;

placing said outlet port in fluid communication with a patient; and

sending said control signals to said actuator to reduce said internal volume of said contractible and expandable enclosure and force a portion of the liquid therapeutic agent within said medication reservoir through said outlet port and into said patient.

21. The method of claim 20, wherein said infusion pump apparatus is implanted or inserted within said patient.

22. The method of claim 20, wherein said control signals are generated based upon a user-activatable switch.

23. The method of claim 22, wherein said user-activatable switch is inserted or implanted within said patient.

24. The method of claim 20, wherein said control signals are generated based on the passage of a predetermined interval of time.

25. The method of claim 20, wherein said control signals are generated based upon input from a chemical sensor that measures a detectable chemical species.