Stents capable of controllably releasing histone deacetylase inhibitors
First Claim
1. A stent device comprising a stent body and one or more HDAC inhibitor depots, said one or more HDAC inhibitor depots being located on or in said stent body, said one or more HDAC inhibitor depots comprising one or more HDAC inhibitors, and said one or more HDAC inhibitor depots being capable of controllably releasing at least one of said one or more HDAC inhibitors.
2 Assignments
0 Petitions
Accused Products
Abstract
A stent device is provided. The stent device includes a stent body and one or more HDAC inhibitor depot(s) provided on or in the stent body, the depot(s) capable of controllably releasing HDAC inhibitor(s). Methods of using the stents in treating and/or preventing restenosis are provided. A delivery system including the stent device and a methods of using the delivery system in treating and/or preventing restenosis are also provided. Kits comprising stents are provided.
129 Citations
67 Claims
- 1. A stent device comprising a stent body and one or more HDAC inhibitor depots, said one or more HDAC inhibitor depots being located on or in said stent body, said one or more HDAC inhibitor depots comprising one or more HDAC inhibitors, and said one or more HDAC inhibitor depots being capable of controllably releasing at least one of said one or more HDAC inhibitors.
-
7. (Cancelled)
-
8. (Cancelled)
-
9. (Cancelled)
-
10. (Cancelled)
-
11. (Cancelled)
-
16. (Cancelled)
-
17. (Cancelled)
-
18. (Cancelled)
-
20. (Cancelled)
-
21. (Cancelled)
-
22. (Cancelled)
-
23. A stent delivery system comprising:
-
(a) a delivery catheter; and
(b) a stent device comprising a stent body and one or more HDAC inhibitor depots, said one or more HDAC inhibitor depots being located on or in said stent body, said one or more HDAC inhibitor depots comprising one or more HDAC inhibitors, and said one or more HDAC inhibitor depots being capable of controllably releasing at least one of said one or more HDAC inhibitors, wherein said stent device is capable of being detachably attached to said delivery catheter. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31)
-
-
32. (Cancelled)
-
33. (Cancelled)
-
34. (Cancelled)
-
35. (Cancelled)
-
36. (Cancelled)
-
37. (Cancelled)
-
38. (Cancelled)
-
39. (Cancelled)
-
40. (Cancelled)
-
41. (Cancelled)
-
42. (Cancelled)
-
43. (Cancelled)
-
44. (Cancelled)
-
45. (Cancelled)
-
46. (Cancelled)
-
47. (Cancelled)
-
48. (Cancelled)
-
49. (Cancelled)
-
50. (Cancelled)
-
51. (Cancelled)
-
52. (Cancelled)
-
53. (Cancelled)
-
54. (Cancelled)
-
55. (Cancelled)
-
56. (Cancelled)
-
57. (Cancelled)
-
58. (Cancelled)
-
59. (Cancelled)
-
60. (Cancelled)
-
61. (Cancelled)
-
62. (Cancelled)
-
63. (Cancelled)
-
64. (Cancelled)
-
65. (Cancelled)
-
66. (Cancelled)
-
67. (Cancelled)
Specification