Modification of lung region flow dynamics using flow control devices implanted in bronchial wall channels
First Claim
1. A flow control device for placement in a bronchial wall of a bronchial passageway in a patient'"'"'s lung, the bronchial wall having inner and outer surfaces, the flow control device comprising:
- a tubular body having first and second ends and a passage therethrough, the tubular body being configured to extend through the bronchial wall with the passage in communication with the bronchial passageway;
a first flange on the first end configured to engage an inner surface of the bronchial wall;
a retainer coupled to the tubular body for retaining the tubular body in the bronchial wall; and
a valve in fluid communication with the passage, the valve configured to allow fluid flow through the passage in a first direction and restrict fluid flow through the passage in a second direction.
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Accused Products
Abstract
A desired fluid flow dynamic to a lung region can be achieved by deploying various combinations of flow control devices and bronchial isolation devices in one or more bronchial passageways that communicate with the lung region. The flow control devices are implanted in channels that are formed in the walls of bronchial passageways of the lung. The flow control devices regulate fluid flow through the channels. The bronchial isolation devices are implanted in lumens of bronchial passageways that communicate with the lung region in order to regulate fluid flow to and from the lung region through the bronchial passageways.
192 Citations
28 Claims
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1. A flow control device for placement in a bronchial wall of a bronchial passageway in a patient'"'"'s lung, the bronchial wall having inner and outer surfaces, the flow control device comprising:
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a tubular body having first and second ends and a passage therethrough, the tubular body being configured to extend through the bronchial wall with the passage in communication with the bronchial passageway;
a first flange on the first end configured to engage an inner surface of the bronchial wall;
a retainer coupled to the tubular body for retaining the tubular body in the bronchial wall; and
a valve in fluid communication with the passage, the valve configured to allow fluid flow through the passage in a first direction and restrict fluid flow through the passage in a second direction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16)
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17. A method of modifying fluid flow through a channel in communication with a bronchial passageway in a patient'"'"'s lung, the bronchial passageway having a wall through which the channel extends, the wall having inner and outer surfaces, the method comprising:
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positioning a flow control device in the bronchial passageway, the flow control device having first and second ends and a passage therebetween;
inserting the first end of the flow control device through the channel in the wall so that the passage is in communication with the bronchial passageway;
securing the flow control device in the wall;
allowing fluid flow in a first direction through the passage to or from the bronchial passageway; and
restricting fluid flow in a second direction through the passage to or from the bronchial passageway. - View Dependent Claims (18, 19, 20, 21, 22)
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23. A method of treating a target region of a patient'"'"'s lung comprising:
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deploying at least one bronchial isolation device in a bronchial passageway of the target region, wherein the bronchial isolation device allows flow in an expiration direction and restricts flow in an inspiration direction through the bronchial passageway; and
forming at least one channel that extends through a wall of a bronchial passageway of the target region, wherein the channel provides a fluid passageway between a location internal to the bronchial passageway and a location external to the bronchial passageway. - View Dependent Claims (24, 25, 26, 27, 28)
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Specification