Apparatus and method for elucidating reaction dynamics of photoreactive compounds from optical signals affected by an external magnetic field
First Claim
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1. An apparatus for elucidating reaction dynamics of photoreactive compounds, comprising:
- means for applying a magnetic field at a region of interest (ROI);
means for illuminating said ROI with a probe beam;
means for collecting light emitted by said probe beam; and
means for analysing said collected light.
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Abstract
An apparatus and method for elucidating reaction dynamics of photoreactive compounds from time-resolved optical signals affected by an external magnetic field. The apparatus includes a coil or magnet for applying a magnetic field at a region of interest (ROI). The apparatus further includes a light or laser for illuminating the ROI with a probe beam. An optical fiber collects light emitted by the probe beam; and a computer analyses the collected light.
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Citations
17 Claims
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1. An apparatus for elucidating reaction dynamics of photoreactive compounds, comprising:
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means for applying a magnetic field at a region of interest (ROI);
means for illuminating said ROI with a probe beam;
means for collecting light emitted by said probe beam; and
means for analysing said collected light. - View Dependent Claims (2, 3, 4, 5, 6, 15, 16, 17)
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7. A method for elucidating reaction dynamics of photoreactive compounds in vivo, comprising the steps of:
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a) irradiating a ROI with a probe beam;
b) recording the tissue fluorescence, phosphorescence and absorption characteristics at at least one wavelength;
c) administering a photoreactive agent;
d) irradiating the ROI with the probe beam;
e) recording the luminescence intensity and lifetime and absorption characteristics of the ROI at at least one wavelength when B=0 Tesla;
f) applying a magnetic field of a predetermined strength;
g) recording the luminescence intensity and lifetime and absorption characteristics of the ROI at at least one wavelength when B>
0 Tesla;
h) repeating steps f) and g) for different magnetic field strengths;
i) turning off said probe beam;
j) processing data obtained; and
k) displaying results obtained by said processing on a display. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14)
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Specification