Iontophoresis device
First Claim
1. An iontophoresis device useful for administering an ionic drug by iontophoresis, said iontophoresis device having an iontophoresis electrode section (active electrode section) and a ground electrode section (inactive electrode section) both of which are connected to a power source, comprising (1) said iontophoresis electrode section comprises:
- (1)-1. an electrode plate connected to a said power source of the same polarity as the charged ions of said ionic drug, (1)-2. an electrolyte-solution-retaining membrane arranged on a front side of said electrode plate and retaining therein an electrolyte solution in such a state that said electrolyte-solution-retaining membrane is impregnated with said electrolyte solution, (1)-3. an ion exchange membrane arranged on a front side of said electrolyte-solution-retaining membrane and selective to ions opposite in polarity to said charged ions of said ionic drug, (1)-4. an ionic-drug-retaining membrane arranged on a front side of said ion exchange membrane and retaining therein said ionic drug in such a state that said ionic-drug-retaining membrane is impregnated with said ionic drug, and (1)-5. an ion-exchange membrane arranged on a front side of said ionic-drug-retaining membrane and selective to ions of the same species as said charged ions of said ionic drug; and
(2) said ground electrode section comprises;
(2)-1. an electrode plate opposite in polarity to said electrode plate in said iontophoresis electrode section, (2)-2. an electrolyte-solution-retaining membrane arranged on a front side of said electrode plate and retaining therein an electrolyte solution in such a state that said electrolyte-solution-retaining membrane is impregnated with said electrolyte solution, and (2)-3. an ion exchange membrane arranged on a front side of said electrolyte-solution-retaining membrane and selective to ions opposite in polarity to said charged ions of said ionic drug.
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Accused Products
Abstract
An iontophoresis device useful for administering an ionic drug by iontophoresis has an iontophoresis electrode section (active electrode section) and a ground electrode section (inactive electrode section) both of which are to be connected to a power source. The iontophoresis device includes elements (members) of both of the electrode sections are all formed of membrane bodies, and includes ion exchange membranes different in ion selectivity, one being selective to ions of the same species as charged ions of the ionic drug and the other to ions different in species from the charged ions of the ionic drug that are arranged in the iontophoresis electrode section, and at least an ion exchange membrane selective to ions opposite to the charged ions of the ionic drug is arranged in the ground electrode section. The iontophoresis device can administer the ionic drug stably over a long period of time at high transport efficiency.
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Citations
26 Claims
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1. An iontophoresis device useful for administering an ionic drug by iontophoresis, said iontophoresis device having an iontophoresis electrode section (active electrode section) and a ground electrode section (inactive electrode section) both of which are connected to a power source, comprising
(1) said iontophoresis electrode section comprises: -
(1)-1. an electrode plate connected to a said power source of the same polarity as the charged ions of said ionic drug, (1)-2. an electrolyte-solution-retaining membrane arranged on a front side of said electrode plate and retaining therein an electrolyte solution in such a state that said electrolyte-solution-retaining membrane is impregnated with said electrolyte solution, (1)-3. an ion exchange membrane arranged on a front side of said electrolyte-solution-retaining membrane and selective to ions opposite in polarity to said charged ions of said ionic drug, (1)-4. an ionic-drug-retaining membrane arranged on a front side of said ion exchange membrane and retaining therein said ionic drug in such a state that said ionic-drug-retaining membrane is impregnated with said ionic drug, and (1)-5. an ion-exchange membrane arranged on a front side of said ionic-drug-retaining membrane and selective to ions of the same species as said charged ions of said ionic drug; and
(2) said ground electrode section comprises;
(2)-1. an electrode plate opposite in polarity to said electrode plate in said iontophoresis electrode section, (2)-2. an electrolyte-solution-retaining membrane arranged on a front side of said electrode plate and retaining therein an electrolyte solution in such a state that said electrolyte-solution-retaining membrane is impregnated with said electrolyte solution, and (2)-3. an ion exchange membrane arranged on a front side of said electrolyte-solution-retaining membrane and selective to ions opposite in polarity to said charged ions of said ionic drug. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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Specification