Apparatus for the classification of physiological events

• US 20050071304A1
• Filed: 09/29/2003
• Published: 03/31/2005
• Est. Priority Date: 09/29/2003
• Status: Abandoned Application

• Current Assignee: Biotronik SE & Company KG
• Original Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Inventors: Schomburg, Richard A.
• Application Number:
  US10/674,280
• Publication Number:
  US 20050071304A1
• Time in Patent Office: Days
• US Class Current: 706/20
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/726 using Wavelet transforms
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: G06F 2218/12 Classification; Matching
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

An apparatus according to the invention for the classification of physiological events on the basis of physiological signals which represent or constitute the physiological events by means of a probabilistic neural network 5 includes a probabilistic neural network 5 which is adapted to receive a set of values representing the physiological signal and which contains a number of event classes which represent physiological events and which are respectively determined by a number of comparative values, which network is adapted on the basis of the comparison of the set of values with the comparative values to implement an association of the physiological signal represented by the set of values with one of the event classes, and an updating unit 10 connected to the probabilistic neural network 5 for updating the comparative values of an event class on the basis of the set of values of at least one physiological signal which has been associated with said event class in a preceding association operation.

Claims

1. An apparatus for the classification of physiological events on the basis of physiological signals, said apparatus comprising:

a probabilistic neural network which is adapted to receive a set of values representing the physiological signal and which contains a number of event classes which represent physiological events and which are respectively determined by a number of comparative values, which network is adapted on the basis of the comparison of the set of values with the comparative values to implement an association of the physiological signal represented by the set of values with one of the event classes, and

an updating unit connected to the probabilistic neural network for updating the comparative values of an event class on the basis of the set of values of at least one physiological signal which has been associated with said event class in a preceding association operation.

2. The apparatus of claim 1, wherein:

the updating unit is so designed that upon updating of the comparative values an average value is formed from a number of value sets which have previously resulted in an association of the physiological signals which they represent with the event class to be updated and wherein the updating operation is effected on the basis of the average value formed in that way.

3. The apparatus of claim 1 wherein:

the updating unit is so designed that upon updating of the comparative values exponential weighting of a number of value sets which have previously resulted in an association of the physiological signals which they represent with the event class to be updated is effected and wherein the updating operation is effected on the basis of the exponentially weighted value sets.

4. The apparatus of claim 3, wherein:

the updating unit is so designed that updating of an event class is effected after the association of a n-th value set with said event class, wherein that defines a predetermined number of value sets.

5. The apparatus of claim 4, wherein:

different values for n are to be associated with different event classes.

6. The apparatus of claim 5, further comprising:

a signal input for the input of a physiological signal; and

a transformation unit which is connected to the signal input for receiving the physiological signal and which is adapted to implement a transformation of the physiological signal in such a way that as the output signal it outputs a number of values representing the physiological signal and based on the transformation operation;

wherein the probabilistic neural network is connected to the transformation unit for receiving the values as the value set.

7. The apparatus of claim 6, wherein:

the transformation unit is adapted for executing the transformation operation on the basis of wavelets and a transformation rule determining the values to be outputted using the wavelets.

10. The apparatus of claim 1, wherein:

the updating unit is so designed that updating of an event class is effected after the association of a n-th value set with said event class, wherein that defines a predetermined number of value sets.

11. The apparatus of claim 2, wherein:

the updating unit is so designed that updating of an event class is effected after the association of a n-th value set with said event class, wherein that defines a predetermined number of value sets.

12. The apparatus of claim 10, wherein:

different values for n are to be associated with different event classes.

13. The apparatus of claim 11, wherein:

different values for n are to be associated with different event classes.

14. The apparatus of claim 1, further comprising:

a signal input for the input of a physiological signal; and

a transformation unit which is connected to the signal input for receiving the physiological signal and which is adapted to implement a transformation of the physiological signal in such a way that as the output signal it outputs a number of values representing the physiological signal and based on the transformation operation;

wherein the probabilistic neural network is connected to the transformation unit for receiving the values as the value set.

15. The apparatus of claim 14, wherein:

the transformation unit is adapted for executing the transformation operation on the basis of wavelets and a transformation rule determining the values to be outputted using the wavelets.

8. An implantable medical device, comprising:

an apparatus for the classification of physiological events on the basis of physiological signals comprising;

a probabilistic neural network which is adapted to receive a set of values representing the physiological signal and which contains a number of event classes which represent physiological events and which are respectively determined by a number of comparative values, which network is adapted on the basis of the comparison of the set of values with the comparative values to implement an association of the physiological signal represented by the set of values with one of the event classes, and

an updating unit connected to the probabilistic neural network for updating the comparative values of an event class on the basis of the set of values of at least one physiological signal which has been associated with said event class in a preceding association operation.

9. The implantable medical advice of claim 8, wherein:

the medical device is in the form of a cardiac pacemaker or defibrillator.