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Cellular compositions and methods of making and using them

  • US 20050074435A1
  • Filed: 12/20/2002
  • Published: 04/07/2005
  • Est. Priority Date: 12/21/2001
  • Status: Active Grant
First Claim
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1. A method for producing an isolated cellular composition comprising or comprising essentially cells with potential or increased potential to form different types of non-hematopoietic cells comprising:

  • (a) obtaining hematopoietic cells;

    (b) enriching the hematopoietic ells for hematopoietic stem cells and progenitor cells by positive or negative selection to obtain an enriched hematopoietic cell preparation. (c) culturing the enriched hematopoietic stem cells and progenitor cells under proliferation conditions so that cells in the preparation develop the potential or an increased potential to form different types of non-hematopoietic cells.

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