Contact lens solution

• US 20050074467A1
• Filed: 01/31/2003
• Published: 04/07/2005
• Est. Priority Date: 02/07/2002
• Status: Abandoned Application

• Current Assignee: Ophtecs Corporation
• Original Assignee: Ophtecs Corporation
• Inventors: Nishimura, Shinji, Fujita, Masaaki, Saito, Fumio, Umeda, Yuzuru, Nakamichi, Chihiro, Tajiri, Motoharu
• Application Number:
  US10/472,443
• Publication Number:
  US 20050074467A1
• Time in Patent Office: Days
• US Class Current: 424/400
• CPC Class Codes: A61L 12/14 Organic compounds not covered by groups A61L12/10 or A61L12/12
• CPC Class Codes: A61L 12/142 Polymeric biguanides
• CPC Class Codes: A61L 12/143 Quaternary ammonium compounds
• CPC Class Codes: C11D 3/0078 Compositions for cleaning contact lenses, spectacles or lenses
• CPC Class Codes: C11D 3/3719 Polyamides or polyimides
• CPC Class Codes: C11D 3/48 Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
• CPC Class Codes: C11D 7/16 Phosphates including polyphosphates
• CPC Class Codes: C11D 7/32 containing nitrogen
• CPC Class Codes: C11D 7/3245 Aminoacids
• CPC Class Codes: C11D 7/3272 Urea, guanidine or derivatives thereof

Abstract

A liquid formulation for contact lenses which comprises polylysine, polyphosphoric acid and/or salt thereof as a substance for suppressing the adhesion of polylysine to a contact lens, nitrogen-containing organic anti-microbial agent excluding polylysine and water. Contact lenses can be cleaned, disinfected and stored simply by soaking them in the liquid formulation without cleaning by digital rubbing or without rinsing before they are worn in eyes.

Claims

1. A liquid formulation for contact lenses which comprises polylysine, polyphosphoric acid and/or salt thereof, nitrogen-containing organic anti-microbial agent (excluding polylysine) and water.

2. The liquid formulation for contact lenses according to claim 1, wherein the polylysine is ε

-polylysine.

3. The liquid formulation for contact lenses according to claim 1, wherein the polyphosphoric acid is at least one selected from the group consisting of pyrophosphoric acid, tripolyphosphoric acid, trimetaphosphoric acid, tetraphosphoric acid, hexametaphosphoric acid and a combination thereof, and the polyphosphate is the salt of at least one of them.

4. The liquid formulation for contact lenses according to claim 1, wherein the nitrogen-containing organic anti-microbial agent is at least one selected from the group consisting of polyhexamethylene biguanide, polyhexamethylene biguanide salt and quaternary ammonium salt.

5. The liquid formulation for contact lenses according to claim 1, wherein the amount of polylysine is 1×

10<sup>−

4</sup> to 2 (w/v) %, the amount of the polyphosphoric acid and/or salt thereof is 1×

10<sup>−

3</sup> to 5 (w/v) % and the amount of the nitrogen-containing organic anti-microbial agent is 1×

10<sup>−

6</sup> to 1 (w/v) % based on the liquid formulation.

6. The liquid formulation for contact lenses according to claim 1, which further comprises at least one additive, selected from the group consisting of buffer, surfactant, viscosity inducing agent and isotonic agent.

7. The liquid formulation for contact lenses according to claim 1, which is used for water content contact lenses.