Device for regeneration of articular cartilage and other tissue
First Claim
1. A device for facilitating healing of voids in tissue comprising, in its dry state, a macrostructure defining void spaces, the macrostructure comprising a polyelectrolytic complex.
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Abstract
An implantable device for facilitating the healing of voids in bone, cartilage and soft tissue is disclosed. A preferred embodiment includes a cartilage region comprising a polyelectrolytic complex joined with a subchondral bone region. The cartilage region, of this embodiment, enhances the environment for chondrocytes to grow articular cartilage; while the subchondral bone region enhances the environment for cells which migrate into that region'"'"'s macrostructure and which differentiate into osteoblasts. A hydrophobic barrier exists between the regions, of this embodiment. In one embodiment, the polyelectrolytic complex transforms to hydrogel, following the implant procedure.
132 Citations
24 Claims
- 1. A device for facilitating healing of voids in tissue comprising, in its dry state, a macrostructure defining void spaces, the macrostructure comprising a polyelectrolytic complex.
Specification