Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms
First Claim
Patent Images
1. An apparatus for making coated dosage forms comprising:
- a) a mold plate;
b) a retention plate;
wherein the mold plate and retention plate define a mold cavity for enclosing a core and having a flow path defined at least in part by an interior surface of said mold plate and the core to be coated; and
c) a nozzle assembly for introducing a flowable material into said mold cavity to coat at least a first portion of said core with said flowable material, said nozzle assembly having a nozzle tip and valve body comprising a valve stem tip, wherein at least a portion of the valve stem tip or nozzle tip are constructed from or coated with a thermally insulative material.
1 Assignment
0 Petitions
Accused Products
Abstract
Systems, methods and apparatuses for manufacturing dosage forms, and to dosage forms made using such systems, methods and apparatuses are provided. A novel injection zero cycle molding module is disclosed. Such modules may be linked, preferably via a selected transfer device, into an overall system for making dosage forms.
120 Citations
40 Claims
-
1. An apparatus for making coated dosage forms comprising:
-
a) a mold plate;
b) a retention plate;
wherein the mold plate and retention plate define a mold cavity for enclosing a core and having a flow path defined at least in part by an interior surface of said mold plate and the core to be coated; and
c) a nozzle assembly for introducing a flowable material into said mold cavity to coat at least a first portion of said core with said flowable material, said nozzle assembly having a nozzle tip and valve body comprising a valve stem tip, wherein at least a portion of the valve stem tip or nozzle tip are constructed from or coated with a thermally insulative material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 13)
-
-
11. An apparatus for making coated dosage forms comprising:
-
a) a first mold plate;
b) a second mold plate;
wherein the first mold plate and second plate define a mold cavity for enclosing a core and having a flow path defined at least in part by an interior surface of said first mold plate and the core to be coated; and
c) a nozzle assembly in said first mold plate and said second mold for introducing a flowable material into said mold cavity to coat at least a portion of said core with said flowable material, said nozzle assemblies having a nozzle tip and valve assembly comprising a valve stem tip, wherein at least a portion of the valve stem tip or nozzle tip are constructed from or coated with a thermally insulative material. - View Dependent Claims (12, 14, 15, 16, 27)
-
-
17. A method for making a dosage form comprising:
-
a) providing a core within a mold cavity formed between a mold plate and a retention plate;
b) injecting a flowable material through a nozzle assembly into said mold cavity to coat at least a first portion of said core with said flowable material, said nozzle assembly having a nozzle tip and valve assembly comprising a valve stem tip, wherein at least a portion of the valve stem tip or nozzle tip are constructed from or coated with a thermally insulative material. - View Dependent Claims (18, 19, 20, 21, 22, 25, 26)
-
-
23. A method for making dosage forms comprising:
-
a) providing within a mold cavity formed between a first mold plate and a second mold plate a core having a coating on a first portion thereof;
b) injecting a flowable material into said mold cavity through a nozzle assembly provided in said first mold plate to coat at least a second portion of said core with said flowable material, said nozzle assembly having a nozzle tip and valve assembly comprising a valve stem tip, wherein at least a portion of the valve stem tip or nozzle tip are constructed from or coated with a thermally insulative material. - View Dependent Claims (24, 28, 29, 30)
-
-
31. A method of making dosage forms, comprising the steps of:
-
a) compressing a powder into a compressed core in a compression module;
b) transferring said compressed core to a zero cycle molding module;
c) molding a flowable material around said compressed core in said zero cycle molding module; and
d) hardening said flowable material so as to form a coating over said compressed core;
wherein steps (a) through (d) are linked together such that essentially no interruption occurs between said steps. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40)
-
Specification