Low extractable, thermoplastic syringe and tip cap
First Claim
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1. A syringe tip cap comprising:
- a body having a first open end, a closed second end and a bore having an internal dimension for mating with a tip of a syringe, said body being made from a polymer composition comprising a thermoplastic cyclic olefin polymer or copolymer and a thermoplastic elastomer and being sufficiently flexible to couple to and seal with the tip of a syringe.
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Accused Products
Abstract
A prefilled syringe and syringe assembly having a syringe and a tip cap are produced from materials that do not interfere with the substance contained in the syringe and enable long term storage. The tip cap is made from a blend of a cyclic olefin polymer or copolymer and a thermoplastic elastomer. The thermoplastic elastomer is blended with the cyclic olefin copolymer in an amount so that the normally stiff and hard cyclic olefin copolymer is flexible and resilient to effectively seal and couple to the tip of a prefilled syringe.
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Citations
36 Claims
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1. A syringe tip cap comprising:
a body having a first open end, a closed second end and a bore having an internal dimension for mating with a tip of a syringe, said body being made from a polymer composition comprising a thermoplastic cyclic olefin polymer or copolymer and a thermoplastic elastomer and being sufficiently flexible to couple to and seal with the tip of a syringe. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A prefillable, low particle, low extractable syringe comprising:
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a syringe assembly including a syringe barrel having a substance receiving chamber and a tip extending from a distal end of said syringe barrel and having a fluid passage extending through said tip, and a plunger received in said syringe barrel, and a tip cap coupled to said tip for closing said tip, said tip cap being sufficiently flexible and resilient to be removably coupled to said tip and form a substantially fluidtight seal with said tip, said tip cap being made from an elastic and flexible polymer composition comprising a thermoplastic cyclic olefin polymer or copolymer and a thermoplastic elastomer. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A prefilled syringe assembly comprising:
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a syringe barrel having a hollow body with a first open end and a tip with a bore extending into said hollow body;
a plunger received in and closing said first open end;
a solution or suspension contained within said syringe barrel to define said prefilled syringe; and
a tip cap removably coupled to said tip, said tip cap being made from a flexible and resilient polymer composition comprising a thermoplastic cyclic olefin polymer or copolymer and a thermoplastic elastomer. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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Specification