Method and apparatus for the delivery of substances to biological components
First Claim
1. A method for the administration of substances to and/or through biological components, comprising exposing the substance to be delivered to a cyclic high impact accelerating movement over a short displacement of amplitude, causing acceleration of the substance, rapid displacement of the substance and driving the substance to and/or through biological components, while isolating the bulk of the targeted biological components from the driving force during delivery.
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Abstract
The invention concerns a method and device for needle-less delivery of substances into or through natural or artificial biological components such as membranes, organelles, cells, tissues, organs, or creatures, by exposing the said biological components to accelerated substances wherein high impact mechanical movement over short distance is used to create acceleration of substances so to drive substances into or through said natural or artificial biological components, while isolating the biological component from the driving force. The mechanical movement is preferably created by an ultrasonic member having a high repetition rate, and the space between accelerating element and biological target is preferably composed of low density compound. The delivery device can be provided with a unit for supplying substance to be delivered, to the mechanical accelerating element. The device can be constructed either as delivery device for superficial tissues, or as an endoscopes laparoscope-like or catheter-like device for delivery in minimally invasive procedures.
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Citations
73 Claims
- 1. A method for the administration of substances to and/or through biological components, comprising exposing the substance to be delivered to a cyclic high impact accelerating movement over a short displacement of amplitude, causing acceleration of the substance, rapid displacement of the substance and driving the substance to and/or through biological components, while isolating the bulk of the targeted biological components from the driving force during delivery.
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52. A device for the administration by acceleration of substances to and/or through biological components comprising:
- at least one acceleration agent capable of giving acceleration stimulus and at least a portion of substance to be delivered.
- View Dependent Claims (68, 69, 70)
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73. A system and method as hereinabove described for the treatment of non-biological components.
Specification