Neural stimulation delivery device with independently moveable delivery structures

• US 20050075681A1
• Filed: 01/31/2003
• Published: 04/07/2005
• Est. Priority Date: 02/01/2002
• Status: Active Grant

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: Rezai, Ali, Sharan, Ashwini
• Granted Patent: US 7,831,308 B2
• Time in Patent Office: Days
• US Class Current: 607/48
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole

Abstract

The present invention relates to a neural stimulation delivery device to deliver electrical and/or chemical stimulation to target sites in the central and peripheral nervous system. The device generally includes a tubular body defining a plurality of ports along the longitudinal axis thereof, a plurality of delivery structures insertable in the body, and a control mechanism in communication with the plurality of delivery structures to independently move each of the plurality of delivery structures through a respective one of the plurality of ports with respect to each other of the plurality of delivery structures. The ability of each delivery structure to be independently moveable through a respective port allows each delivery structure to be selectively advanced or retracted independent of the movement of another delivery structure.

Claims

1. A stimulation delivery device for stimulating neural tissue comprising:

a body having a proximal end and a distal end and defining a plurality of ports along the longitudinal axis thereof between the proximal end and the distal end of the body; and

a plurality of delivery structures insertable within the body, each of the plurality of delivery structures independently moveable through a respective one of the plurality of ports.

2. The device of claim 1, wherein the plurality of delivery structures is electrodes.

3. The device of claim 1, wherein the plurality of delivery structures is a plurality of leads, each of the plurality of leads having at least one delivery element thereon, the at least one delivery element being an at least one electrode.

4. The device of claim 3, wherein the at least on electrode of each of the plurality of leads is selectively powerable.

5. The device of claim 1, wherein the plurality of delivery structures is catheters, the catheters having at least one delivery element thereon, the at least one delivery element being an at least one drug port.

6. The device of claim 1, further comprising a first delivery element disposed on the body, the first delivery element being either an electrode or drug port.

7. The device of claim 6, further including a second delivery element disposed on the body, the second delivery element being either an electrode or drug port.

8. The device of claim 7, wherein the first delivery element and the second delivery element are electrodes, the electrodes being selectively powerable.

9. The device of claim 1, further comprising a control mechanism in communication with the plurality of delivery structures to independently move each of the plurality of delivery structures through a respective one of the plurality of ports with respect to each other of the plurality of delivery structures.

10. The device of claim 1, wherein the plurality of delivery structures is exitable through respective ones of the plurality of ports at an angle of less than 90 degrees with respect to the longitudinal axis of the body.

11. The device of claim 1, wherein the body further defines at least one port at the distal end thereof.

13. The device of claim 1, wherein the plurality of delivery structures is extendable between about 1 to about 10 millimeters from respective ones of the plurality of ports.

14. The device of claim 1, wherein the plurality of delivery structures is capable of non-destructively stimulating neural tissue.

12. The device of claim, wherein at least one delivery structure is extendable through the at least one port.

15. A stimulation delivery device for stimulating neural tissue comprising:

a body having a proximal end and a distal end, the body defining an annular arrangement of a first plurality of ports between the proximal end and the distal end about a plane transverse to the longitudinal axis of the body; and

a first plurality of delivery structures insertable in the body, each of the first plurality of delivery structures independently moveable through a respective one of the first plurality of ports.

16. The device of claim 15, wherein each of the first plurality of ports is situated 90 degrees apart from each other in the same annular plane.

17. The device of claim 15, wherein the body further defines an annular arrangement of a second plurality of ports between the first plurality of ports and the proximal end of the body about a plane transverse to the longitudinal axis of the body.

18. The device of claim 17, wherein each of the second plurality of ports is situated 90 degrees apart from each other in the same annular plane.

19. The device of claim 18, further comprising a second plurality of delivery structures insertable in the body.

20. The device of claim 19, wherein the each of the second plurality of delivery structures are independently moveable through a respective one of the second plurality of ports.

21. The device of claim 15, further comprising a first delivery element disposed on the body.

22. The device of claim 21, wherein the first delivery element extends approximately 360 degrees about the body.

23. The device of claim 21, wherein the first delivery element is an electrode divided into segments, each segment being selectively powerable.

24. The device of claim 15, wherein the body further defines at least one port at the distal end thereof.

25. The device of claim 24, wherein at least one delivery structure is extendable through the at least one port.

26. A stimulation delivery device for stimulating neural tissue comprising:

a body having a proximal end and a distal end, the body defining an semi-annular arrangement of a first plurality of ports between the proximal end and the distal end about a plane transverse to the longitudinal axis of the body; and

a first plurality of delivery structures insertable in the body, each of the first plurality of delivery structures independently moveable through a respective one of the first plurality of ports.

27. The device of claim 26, wherein each of the first plurality of ports is situated 45 degrees apart from each other in the same annular plane.

28. The device of claim 26, wherein the body further defines a semi-annular arrangement of a second plurality of ports between the first plurality of ports and the proximal end of the body.

29. The device of claim 28, wherein each of the second plurality of ports is situated 45 degrees apart from each other in the same annular plane.

30. The device of claim 28, further comprising a second plurality of delivery structures insertable in the body.

31. The device of claim 30, wherein each of the second plurality of delivery structures is independently moveable through a respective one of the second plurality of ports.

32. The device of claim 26, further comprising a first delivery element disposed on the body.

33. The device of claim 32, wherein the first delivery element extends approximately 360 degrees about the body.

34. The device of claim 33, wherein the first delivery element is an electrode divided into segments, each segment being selectively powerable.

35. The device of claim 26, wherein the body further defines at least one port at the distal end thereof.

36. The device of claim 35, wherein at least one delivery structure is extendable through the at least one port.

37. A stimulation delivery device for stimulating neural tissue comprising:

a body having a proximal end and a distal end and defining a plurality of ports at the distal end thereof; and

a plurality of delivery structures insertable within the body, each of the plurality of delivery structures independently moveable through a respective one of the plurality of ports.

38. A stimulation delivery system for stimulating neural tissue of the brain to affect a neurological condition comprising:

a stimulation delivery device comprising a body having a proximal end and a distal end and defining a plurality of ports along the longitudinal axis thereof between the proximal end and the distal end of the body; and

a plurality of delivery structures insertable within the body; and

a control mechanism in communication with the stimulation delivery device to independently move each of the plurality of delivery structures through a respective one of the plurality of ports.

39. The system of claim 38, wherein the control mechanism comprises a gear and clutch assembly.

40. The system of claim 39, wherein the gear and clutch assembly is motorized.

41. The system of claim 38, wherein the control mechanism comprises a rack and pinion gearing assembly.

42. The system of claim 41, wherein the rack and pinion gearing assembly comprises:

a carrier;

a plurality of shafts insertable within the carrier, each of the plurality of shafts having a proximal end and a distal end, each of the plurality of shafts engagable with a corresponding one of the plurality of delivery structures at the distal end of each of the plurality of shafts; and

a plurality of drivers each engagable with a corresponding one of the plurality of shafts, such that upon manipulation of each of the plurality of drivers, the corresponding one of the plurality of delivery structures advances or retracts through the respective one of the plurality of ports.

43. The system of claim 42, wherein each of the plurality of drivers are threadably engagable with a corresponding one of the plurality of shafts.

44. The system of claim 38, further comprising a microelectrode recording device in communication with the stimulation delivery device.

45. The system of claim 38, further comprising at least one sensor in communication with the stimulation delivery device to detect a characteristic of the neurological condition being affecting.

46. The system of claim 38, further comprising a navigation system to detect the position of the stimulation delivery device within the brain.