Methods and apparatus for sample mixing
First Claim
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1. An apparatus for mixing fluids, said apparatus comprising:
- (a) a housing having an interior with capillary dimensions and (b) a pressure activated mechanism in fluid communication with said interior, said pressure activated mechanism being activatable to cause reciprocal motion of fluid in said interior resulting in mixing of fluid in said interior.
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Abstract
Apparatus and methods for mixing fluids are disclosed. An apparatus comprises a housing or channel having an interior with capillary dimensions and a pressure activated mechanism in fluid communication with the interior. The pressure activated mechanism is activatable to cause motion of fluid in the interior of the housing thereby mixing the fluid in the interior. An apparatus may comprise an activating mechanism for activating the pressure activated mechanism. Typically, at least a portion of the interior of the housing comprises a linear array of features for conducting chemical reactions. Optionally, an apparatus comprises a fluid dispensing device.
31 Citations
26 Claims
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1. An apparatus for mixing fluids, said apparatus comprising:
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(a) a housing having an interior with capillary dimensions and (b) a pressure activated mechanism in fluid communication with said interior, said pressure activated mechanism being activatable to cause reciprocal motion of fluid in said interior resulting in mixing of fluid in said interior. - View Dependent Claims (2, 3, 4, 5, 6, 7, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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8. An apparatus for conducting hybridization reactions, said apparatus comprising:
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(a) a housing having an interior with capillary dimensions, said interior comprising a linear microarray of biopolymers for conducting hybridization reactions, (b) a compressible member in fluid communication with said interior, said compressible member being deflectable to cause reciprocal motion of fluid in said interior resulting in mixing of fluid, and (c) a deflection mechanism for deflecting said compressible member. - View Dependent Claims (9, 10)
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Specification