Cerebral perfusion augmentation
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Abstract
Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is then located downstream from the takeoff of the brachiocephalic artery. The device is operated to at least partially obstruct blood flow in the aorta during systole and diastole. A physiologic parameter can be measured. The device can then be adjusted to modify the degree of obstruction based on the measured physiologic parameter.
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Citations
40 Claims
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1-20. -20. (canceled)
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21. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region;
locating the expandable member in the abdominal aorta;
expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole;
measuring a physiologic parameter; and
adjusting the expansion of the expandable member based on the measured physiologic parameter. - View Dependent Claims (22, 23, 24, 25)
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26. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region;
locating the expandable member in the abdominal or thoracic aorta;
expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole;
measuring a physiologic parameter; and
adjusting the expansion of the expandable member based on the measured physiologic parameter. - View Dependent Claims (27, 28, 29, 30)
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31. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region;
locating the expandable member in the aorta inferior to the heart;
expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole;
measuring a physiologic parameter; and
adjusting the expansion of the expandable member based on the measured physiologic parameter. - View Dependent Claims (32, 33, 34, 35)
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36. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region;
locating the expandable member in the descending aorta;
expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole for a sustained period without occluding the aorta;
measuring a physiologic parameter; and
adjusting the expansion of the expandable member based on the measured physiologic parameter. - View Dependent Claims (37, 38, 39, 40)
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Specification