Endoluminal prosthesis endoleak management
First Claim
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1. A method of reducing a blood flow into a perigraft space between an endovascular graft and a body lumen wall, the method comprising:
- accessing the perigraft space with a delivery device; and
delivering an embolic material into the perigraft space with the delivery device, wherein the embolic material comprises polyethylene glycol diacrylate, pentaerthyritol tetra 3(mercaptopropionate), and a buffer.
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Abstract
The present invention provides methods and compositions for managing endoleaks in a perigraft space around an endovascular graft. In one embodiment, a blood flow through the endovascular graft is temporarily reduced and an embolic material is delivered into the perigraft space while the blood flow through the endovascular graft is reduced. The embolic material may comprise polyethylene glycol diacrylate, pentaerthyritol tetra 3(mercaptopropionate), and a buffer.
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Citations
55 Claims
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1. A method of reducing a blood flow into a perigraft space between an endovascular graft and a body lumen wall, the method comprising:
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accessing the perigraft space with a delivery device; and
delivering an embolic material into the perigraft space with the delivery device, wherein the embolic material comprises polyethylene glycol diacrylate, pentaerthyritol tetra 3(mercaptopropionate), and a buffer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A system for depositing an embolic material in a perigraft space between an endovascular graft and a body lumen wall, the system comprising:
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a delivery device configured to access the perigraft space;
an occlusion assembly that is configured to substantially reduce a blood flow through the endovascular graft; and
an embolic material that is delivered to the perigraft space with the delivery device, wherein the embolic material comprises polyethylene glycol diacrylate, pentaerthyritol tetra 3(mercaptopropionate), and a buffer. - View Dependent Claims (32, 33, 34, 35, 36, 44)
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- 37. The system of claim 37 wherein the buffer comprises glycylglycine.
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45. A kit for depositing an embolic material in a perigraft space between an endovascular graft and a body lumen wall, the kit comprises:
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a delivery device configured to access the perigraft space; and
an embolic material comprising polyethylene glycol diacrylate, pentaerthyritol tetra 3(mercaptopropionate), and a buffer. - View Dependent Claims (46, 47, 48, 49, 50, 51, 52, 53, 54, 55)
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Specification