Apparatus and method for an ultrasonic medical device to treat coronary thrombus bearing lesions

• US 20050096669A1
• Filed: 10/28/2004
• Published: 05/05/2005
• Est. Priority Date: 10/05/1999
• Status: Abandoned Application

• Current Assignee: Cybersonics, Inc
• Original Assignee: OmniSonics Medical Technologies, Inc.
• Inventors: Rabiner, Robert A., Hare, Bradley A., Kelley, Craig T.
• Application Number:
  US10/976,268
• Publication Number:
  US 20050096669A1
• Time in Patent Office: Days
• US Class Current: 606/128
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/22012 in direct contact with, or very close to, the obstruction or concrement for removing obstructions in blood vessels by laser A61B18/245
• CPC Class Codes: A61B 2017/00137 Details of operation mode
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/22002 preventing restenosis
• CPC Class Codes: A61B 2017/22007 Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
• CPC Class Codes: A61B 2017/22008 used or promoted
• CPC Class Codes: A61B 2017/22015 with details of the transmission member
• CPC Class Codes: A61B 2017/22018 segmented along its length
• CPC Class Codes: A61B 2017/22051 with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation A61B2017/22048, A61B2017/3486 take precedence
• CPC Class Codes: A61B 2017/293 with means preventing relative rotation between the shaft and the actuating rod
• CPC Class Codes: A61B 2017/320069 for ablating tissue
• CPC Class Codes: A61B 2017/320084 Irrigation sleeves
• CPC Class Codes: A61B 2017/320089 node location
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2018/00982 combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61B 2217/007 with irrigation system
• CPC Class Codes: A61N 2007/0008 Destruction of fat cells
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

An apparatus and method for using an ultrasonic medical device to treat coronary thrombus bearing lesions comprises an ultrasonic probe, a transducer, a coupling engaging a proximal end of the ultrasonic probe to a distal end of the transducer and an ultrasonic energy source engaged to the transducer. The ultrasonic probe is inserted into a vasculature in communication with the coronary thrombus bearing lesion. The ultrasonic energy source produces energy that is transmitted to the transducer, which generates a transverse ultrasonic vibration along the ultrasonic probe. The transverse ultrasonic vibration creates a plurality of transverse nodes and a plurality of transverse anti-nodes along the longitudinal axis of the ultrasonic probe, creating cavitation along a portion of the longitudinal axis of the ultrasonic probe to ablate the coronary thrombus bearing lesion.

Claims

1. An ultrasonic medical device for treating a coronary thrombus bearing lesion comprising:

an ultrasonic probe having a proximal end, a distal end and a longitudinal axis therebetween;

a transducer creating a transverse ultrasonic vibration along at least a portion of the longitudinal axis of the ultrasonic probe;

a coupling engaging the proximal end of the ultrasonic probe to a distal end of the transducer; and

an ultrasonic energy source engaged to the transducer,

wherein the transverse ultrasonic vibration generates a plurality of transverse nodes and a plurality of transverse anti-nodes along at least a portion of the longitudinal axis of the ultrasonic probe, creating cavitation in a medium surrounding the ultrasonic probe to treat the coronary thrombus bearing lesion.

2. The ultrasonic medical device of claim 1 wherein the ultrasonic probe comprises a material that allows the ultrasonic probe to be bent, deflected and flexed.

3. The ultrasonic medical device of claim 1 wherein the ultrasonic probe comprises a diameter that enables insertion into a coronary artery.

4. The ultrasonic medical device of claim 1 wherein a diameter of the ultrasonic probe has a uniform diameter from the proximal end to the distal end.

5. The ultrasonic medical device of claim 1 wherein a diameter of the ultrasonic probe varies from the proximal end to the distal end.

6. The ultrasonic medical device of claim 1 wherein a cross section of the ultrasonic probe is approximately circular.

7. The ultrasonic medical device of claim 1 wherein the transverse ultrasonic vibration generates acoustic energy in a medium surrounding the ultrasonic probe.

8. The ultrasonic medical device of claim 1 wherein the ultrasonic energy source delivers energy in a frequency range from about 10 kHz to about 100 kHz.

9. The ultrasonic medical device of claim 1 wherein the ultrasonic energy source provides an electrical energy to the transducer at a resonant frequency of the transducer by finding the resonant frequency of the transducer.

10. The ultrasonic medical device of claim 1 wherein the ultrasonic probe is disposable.

11. The ultrasonic medical device of claim 1 further comprising at least one radiopaque marker located along the longitudinal axis of the ultrasonic probe.

12. The ultrasonic medical device of claim 11 wherein the radiopaque marker allows the ultrasonic probe to be visualized through a fluoroscopic procedure.

13. The ultrasonic medical device of claim 1 wherein the ultrasonic probe contains a super-elastic alloy.

14. An ultrasonic medical device for ablating a coronary thrombus bearing lesion comprising:

an ultrasonic probe having a proximal end, a distal end terminating in a probe tip and a longitudinal axis between the proximal end and the distal end;

a transducer that converts electrical energy into mechanical energy, creating a transverse ultrasonic vibration along the longitudinal axis of the ultrasonic probe; and

a coupling engaging the proximal end of the ultrasonic probe to a distal end of the transducer,

wherein the transverse ultrasonic vibration produces a plurality of transverse nodes and a plurality of transverse anti-nodes along a portion of the longitudinal axis of the ultrasonic probe.

15. The ultrasonic medical device of claim 14 wherein the ultrasonic probe supports the transverse ultrasonic vibration when flexed.

16. The ultrasonic medical device of claim 14 wherein the ultrasonic probe has a flexibility allowing the ultrasonic probe to be deflected and articulated.

17. The ultrasonic medical device of claim 14 wherein the transverse ultrasonic vibration along the longitudinal axis of the ultrasonic probe interacts with a medium surrounding the ultrasonic probe to create an acoustic wave in the medium.

18. The ultrasonic medical device of claim 14 wherein the transverse ultrasonic vibration of the ultrasonic probe produces cavitation in a medium surrounding the ultrasonic probe to ablate the coronary thrombus bearing lesion.

19. The ultrasonic medical device of claim 14 wherein an ultrasonic energy source engages the transducer to provide the electrical energy to the transducer.

20. The ultrasonic medical device of claim 14 further comprising at least one radiopaque marker located along the longitudinal axis of the ultrasonic probe.

21. The ultrasonic medical device of claim 20 wherein the radiopaque marker allows the ultrasonic probe to be visualized through a fluoroscopic procedure.

22. The ultrasonic medical device of claim 14 wherein the ultrasonic probe contains a super-elastic alloy.

23. A method of resolving a coronary thrombus bearing lesion comprising:

providing an ultrasonic medical device comprising an ultrasonic probe having a proximal end, a distal end and a longitudinal axis therebetween;

navigating the ultrasonic probe adjacent to the coronary thrombus bearing lesion;

placing the ultrasonic probe in communication with the coronary thrombus bearing lesion; and

activating an ultrasonic energy source engaged to the ultrasonic probe to generate a transverse ultrasonic vibration along at least a portion of the longitudinal axis of the ultrasonic probe,

wherein the transverse ultrasonic vibration creates a plurality of transverse nodes and a plurality of transverse anti-nodes along a portion of the longitudinal axis of the ultrasonic probe.

24. The method of claim 23 further comprising generating acoustic energy in a medium surrounding the ultrasonic probe through the transverse ultrasonic vibration of the ultrasonic probe.

25. The method of claim 23 further comprising sweeping the ultrasonic probe along the coronary thrombus bearing lesion.

26. The method of claim 23 further comprising moving the ultrasonic probe back and forth along the coronary thrombus bearing lesion.

27. The method of claim 23 further comprising rotating the ultrasonic probe along the coronary thrombus bearing lesion.

28. The method of claim 23 further comprising providing an electrical energy to a transducer at a resonant frequency of the transducer by the ultrasonic energy source determining the resonant frequency of the transducer.

29. The method of claim 23 further comprising delivering ultrasonic energy in a frequency range from about 10 kHz to about 100 kHz by the ultrasonic energy source.

30. The method of claim 23 further comprising providing the ultrasonic probe having a flexibility allowing the ultrasonic probe to be deflected and articulated.

31. The method of claim 23 further comprising viewing a radiopaque marker on the ultrasonic probe using a fluoroscopic procedure.

32. The method of claim 23 wherein the ultrasonic probe contains a super-elastic alloy.

33. A method of ablating a coronary thrombus bearing lesion in a coronary artery of a vasculature comprising:

providing an ultrasonic medical device comprising an ultrasonic probe having a proximal end, a distal end terminating in a probe tip, and a longitudinal axis between the proximal end and the distal end;

inserting the ultrasonic probe in an insertion point in the vasculature;

moving the ultrasonic probe to place the ultrasonic probe in communication with the coronary thrombus bearing lesion in the coronary artery; and

activating an ultrasonic energy source engaged to the ultrasonic probe to produce an electric signal that drives a transducer of the ultrasonic medical device to produce a transverse ultrasonic vibration of the ultrasonic probe,

wherein the transverse ultrasonic vibration produces cavitation in a medium surrounding the ultrasonic probe to ablate the coronary thrombus bearing lesion.

34. The method of claim 33 further comprising transmitting a transverse wave from the transverse ultrasonic vibration along the longitudinal axis of the ultrasonic probe to create an acoustic wave in the medium surrounding the ultrasonic probe.

35. The method of claim 33 further comprising producing a plurality of transverse nodes and a plurality of transverse anti-nodes along a portion of the longitudinal axis of the ultrasonic probe by the transverse ultrasonic vibration.

36. The method of claim 35 wherein the plurality of transverse nodes are points of a minimum transverse ultrasonic vibration.

37. The method of claim 35 wherein the plurality of transverse anti-nodes are points of a maximum transverse ultrasonic vibration.

38. The method of claim 33 wherein the ultrasonic probe is for a single use on a single patient.

39. The method of claim 33 further comprising delivering ultrasonic energy in a frequency range of about 10 kHz to about 100 kHz by the ultrasonic energy source.

40. The method of claim 33 further comprising viewing a radiopaque marker on the ultrasonic probe using a fluoroscopic procedure.

41. The method of claim 33 wherein the ultrasonic probe contains a super-elastic alloy.

42. A method of resolving a coronary thrombus bearing lesion comprising:

providing an ultrasonic medical device comprising an ultrasonic probe having a proximal end, a distal end and a longitudinal axis therebetween, wherein the ultrasonic probe comprises at least one radiopaque marker;

navigating the ultrasonic probe adjacent to the coronary thrombus bearing lesion;

viewing the ultrasonic probe using a fluoroscopic procedure;

placing the ultrasonic probe in communication with the coronary thrombus bearing lesion; and

activating an ultrasonic energy source engaged to the ultrasonic probe to generate a transverse ultrasonic vibration along at least a portion of the longitudinal axis of the ultrasonic probe,

wherein the transverse ultrasonic vibration creates a plurality of transverse nodes and a plurality of transverse anti-nodes along a portion of the longitudinal axis of the ultrasonic probe.