Antibacterial composition

• US 20050101678A1
• Filed: 09/08/2003
• Published: 05/12/2005
• Est. Priority Date: 08/14/2000
• Status: Abandoned Application

• Current Assignee: Andreas Natsch
• Original Assignee: Andreas Natsch
• Inventors: Natsch, Andreas
• Application Number:
  US10/657,345
• Publication Number:
  US 20050101678A1
• Time in Patent Office: Days
• US Class Current: 514/715
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 31/06 Oxygen or sulfur directly attached to a cycloaliphatic ring system
• CPC Class Codes: A01N 49/00 Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group , wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group , wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof containing hydrocarbons A01N27/00
• CPC Class Codes: A61K 31/075 Ethers or acetals
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin

Abstract

The present invention relates to an antibacterial composition containing a compound of formula I
wherein R is a residue of the formula II
and R is located at position 2, 3, or 6, and R¹ is hydrogen; or R is located at position 4, and R¹ is hydrogen or methoxy; or R is located at position 5, and R₁ is methoxy. The present invention also relates to the use of the composition in personal care products and methods of making personal care products employing the composition. The antibacterial composition is active against Corynebacteria, Staphylococci, and Brevibacteria. It can therefore inhibit formation of different kinds of body malodor.

Claims

1. A method of providing antibacterial activity, to a patient in need thereof, by administering an antibacterially effective amount of a composition comprising one or more compound(s) of formula I

2. The method of claim 1, wherein the composition contains the compound 2-methoxy-4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol.

3. The method of claim 1, wherein the composition contains the compound 2-methoxy-5-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol).

4. The method of claim 1, wherein the composition comprises one of more compound(s) that are a mixture of at least 2-methoxy-4-(5,5,6-trimethyl-bicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol and 2-methoxy-5-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol.

5. The method of claim 1, wherein the composition comprises of 0.1 to 1% by weight of the compound of formula I.

6. The method of claim 1, wherein the composition comprises of 0.3 to 0.6% by weight of the compound of formula I.

7. The method of claim 1, wherein the composition further comprises of 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol.

8. The method of claim 1, wherein the composition contains a perfume, about 10 to about 80% by weight of which perfume is composed of a compound of formula I.

9. The method of claim 1, wherein the composition contains a perfume, about 10 to about 80% by weight of which perfume is composed of a compound of formula I, and wherein the compound is the only antibacterial agent in the composition.

10. The method of claim 1, wherein the composition contains a perfume, about 10 to about 80% by weight of which perfume is composed of a compound of formula I, and from about 5 to about 50% by weight of the composition is 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol.

11. The method of claim 1, wherein the composition further comprises of an ingredient selected from the group consisting of water, dipropylene glycol, propylene glycol, and combinations thereof.

12. The method of claim 1, wherein the antibacterial activity results in reduction of malodor.

13. The method of claim 1, wherein the antibacterial activity results in the treatment of acne.

14-18. -18. (canceled)