Antimicrobial packaged medical device and method of preparing same
First Claim
1. An antimicrobial suture produced according to the steps of:
- positioning a suture and an antimicrobial agent source within a package, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; and
subjecting the package, the suture and the antimicrobial agent source to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the suture, thereby substantially inhibiting bacterial colonization on the suture.
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Accused Products
Abstract
A packaged medical device produced according to the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device. Alternatively, the packaged medical device is produced according to the steps of positioning a medical device within a package; exposing the package having the medical device to an antimicrobial agent source; and subjecting the package having the medical device and the antimicrobial agent source to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device within the package, thereby substantially inhibiting bacterial colonization on the medical device.
76 Citations
19 Claims
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1. An antimicrobial suture produced according to the steps of:
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positioning a suture and an antimicrobial agent source within a package, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; and
subjecting the package, the suture and the antimicrobial agent source to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the suture, thereby substantially inhibiting bacterial colonization on the suture.
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2. An antimicrobial suture assembly having a suture and at least one packaging component produced according to the steps of:
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positioning a suture assembly and an antimicrobial agent source within a package, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; and
subjecting the package, the suture assembly and the antimicrobial agent source to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the suture, thereby substantially inhibiting bacterial colonization on the suture assembly.
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3. An antimicrobial packaged medical device produced according to the steps of:
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positioning a medical device and an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; and
subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer at least an effective amount of the antimicrobial agent from the antimicrobial agent source to inner surface of the package and the medical device, thereby substantially inhibiting bacterial colonization on the inner surface of the package and the medical device. - View Dependent Claims (4, 5, 6, 7, 8)
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9. A method for making an antimicrobial suture comprising the steps of:
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positioning a suture and an antimicrobial agent source within a package, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; and
subjecting the package, the suture and the antimicrobial agent source to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the suture, thereby substantially inhibiting bacterial colonization on the suture. - View Dependent Claims (10)
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11. A method of making an antimicrobial medical device comprising the steps of:
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positioning a medical device and an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof within the package;
subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device. - View Dependent Claims (12, 13, 14, 15, 16)
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17. A method for making an antimicrobial medical device comprising the steps of:
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exposing a medical device to an antimicrobial agent source; and
subjecting the medical device and the antimicrobial agent source to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device. - View Dependent Claims (18)
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19. An antimicrobial packaged medical device having an effective amount of antimicrobial agent for at least 6 months after sterilization and packaging, and before opening and use in a surgical procedure.
Specification