Composition and apparatus for transdermal delivery
First Claim
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1. A composition for coating a transdermal delivery device having stratum corneum-piercing microprojections comprising a formulation of a biologically active agent and a viscosity-enhancing counterion, wherein said formulation has a therapeutically effective concentration of said biologically active agent.
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Abstract
A formulation for coating a transdermal delivery device having a plurality of stratum corneum-piercing microprojections, the formulation including a biologically active agent and at least one viscosity-enhancing counterion. Preferably, the formulation has a viscosity in the range of about 20-200 cp.
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Citations
28 Claims
- 1. A composition for coating a transdermal delivery device having stratum corneum-piercing microprojections comprising a formulation of a biologically active agent and a viscosity-enhancing counterion, wherein said formulation has a therapeutically effective concentration of said biologically active agent.
- 19. An apparatus for transdermally delivering a biologically active agent to a subject, comprising a microprojection member having a plurality of microprojections that are adapted to pierce said subjects stratum corneum, said microprojection member including a biocompatible coating having at least one biologically active agent, wherein said coating is formed from a formulation having at least one viscosity-enhancing counterion.
Specification