Delivery of polymer conjugates of therapeutic peptides and proteins via coated microprojections
First Claim
1. An apparatus for transdermally delivering a biologically active agent to a patient comprising a microprojection member including a plurality of stratum corneum-piercing microprojections having a biocompatible coating disposed thereon, said biocompatible coating including a biologically active agent selected from the group consisting of peptide and protein conjugates.
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Accused Products
Abstract
An apparatus for transdermally delivering a biologically active agent to a patient comprising a microprojection member having a plurality of microprojections that are adapted to pierce the stratum comeum of the patient, the microprojection member having a biocompatible coating disposed thereon that includes a biologically active agent selected from the group consisting of peptide and protein conjugates.
77 Citations
13 Claims
- 1. An apparatus for transdermally delivering a biologically active agent to a patient comprising a microprojection member including a plurality of stratum corneum-piercing microprojections having a biocompatible coating disposed thereon, said biocompatible coating including a biologically active agent selected from the group consisting of peptide and protein conjugates.
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10. A method for transdermally delivering a biologically active agent to a patient, comprising the steps of:
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providing a microprojection member having a plurality of microprojections that are adapted to pierce said patient'"'"'s stratum comeum;
coating said microprojection member with a coating formulation having said biologically active agent to form a biocompatible coating, wherein said biologically active agent is selected from the group consisting of peptide and protein conjugates; and
applying said microprojection member to said patient'"'"'s skin, whereby said microprojection members pierce said stratum comeum and deliver said biologically active agent. - View Dependent Claims (11, 12, 13)
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Specification