Pulse wave analyzing method, pulse wave analyzing software, and so forth

• US 20050107710A1
• Filed: 04/23/2003
• Published: 05/19/2005
• Est. Priority Date: 04/24/2002
• Status: Abandoned Application

• Current Assignee: Colin Medical Technology Corporation (Omron Corporation)
• Original Assignee: Colin Medical Technology Corporation (Omron Corporation)
• Inventors: Nakayama, Ryu
• Application Number:
  US10/512,310
• Publication Number:
  US 20050107710A1
• Time in Patent Office: Days
• US Class Current: 600/500
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/0285 Measuring or recording phase velocity of blood waves
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/6828 Leg

Abstract

An object of the present invention is to provide a pulse wave analyzing software and a pulse wave analyzing apparatus each of which can extract, from a pulse wave, more information related to an artery.

When a series of formulas developed by the Inventor are applied to pulse wave data, electrocardiogram data, and phonocardiogram data that are measured as time elapses, new parameters related to an artery (e.g., a volume elasticity modulus (Km), a Young'"'"'s modulus (E_A), etc.) can be calculated. These parameters can be used to evaluate functions of a living being in a non-invasive, accurate, easy, and quick fashion.

Claims

1. A pulse wave analyzing software characterized by applying a rheological analysis to pulse wave data measured at two or more different portions of a living being and thereby calculating at least one parameter selected from an effective circulating volume (ECV, Ve) and a Young'"'"'s modulus (E).

2. The pulse wave analyzing software according to claim 1, wherein the effective circulating volume (ECV, Ve) is given by a following formula A:

Ve=ρ

C²m·

Δ

Vst_mean/mPm 

 

Formula A

(where ρ

is a density;

Cm is a mean pulse wave velocity;

Δ

Vst_mean is a stroke volume; and

mPm is a main mean blood pressure),

and wherein the Young'"'"'s modulus (E) is given by a following formula B or following formulas C;

E_A=2ρ

R_o·

C²m/h_A 

 

Formula B

(where E_A is a Young'"'"'s modulus of an aorta;

R_o is an outer radius of the artery; and

h_A is a wall thickness of the artery),

E_ru=2ρ

r_oruC²_ru/h_ru
E_lu=2ρ

r_oluC²_lu/h_lu
E_rl=2ρ

r_orlC²_rl/h_rl
E_ll=2ρ

r_ollC²_ll/h_ll 

 

Formula C

(where suffixes “

ru”

, “

lu”

, “

rl”

, and “

ll”

mean a right upper limb, a left upper limb, a right lower limb, and a left lower limb, respectively;

r_o is an outer radius of an artery of a limb;

C is a pulse wave velocity; and

h is a wall thickness of the artery).

3. A computer capable of implementing the pulse wave analyzing software according to claim 1.

4. A pulse wave analyzing apparatus characterized by including a blood pressure measuring device capable of measuring pulse wave data at two or more different portions of a living being;

an action potential measuring device capable of measuring an action potential of a heart of the living being;

a heart sound measuring device capable of measuring a heart sound of the living being; and

the computer according to claim 3.

6. A computer capable of implementing the pulse wave analyzing software according to claim 2.

5. A pulse wave analyzing method characterized by applying a rheological analysis to pulse wave data measured at two or more different portions of a human being and thereby calculating at least one parameter selected from an effective circulating volume (ECV, Ve) and a Young'"'"'s modulus (E),

wherein the effective circulating volume (ECV, Ve) is given by a following formula A:

Ve=ρ

C²m·

Δ

Vst_mean/mPm 

 

Formula A

(where ρ

is a density;

Cm is a mean pulse wave velocity;

Δ

Vst_mean is a stroke volume; and

mPm is a main mean blood pressure),

and wherein the Young'"'"'s modulus (E) is given by a following formula B or following formulas C;

E_A=2ρ

R_o·

C²m/h_A 

 

Formula B

(where E_A is a Young'"'"'s modulus of an aorta;

R_o is an outer radius of the artery; and

h_A is a wall thickness of the artery),

E_ru=2ρ

r_oruC²_ru/h_ru
E_lu=2ρ

r_oluC²_lu/h_lu
E_rl=2ρ

r_orlC²_rl/h_rl
E_ll=2ρ

r_ollC²_ll/h_ll 

 

Formula C

(where suffixes “

ru”

, “

lu”

, “

rl”

, and “

ll”

mean a right upper limb, a left upper limb, a right lower limb, and a left lower limb, respectively;

r_o is an outer radius of an artery of a limb;

C is a pulse wave velocity; and

h is a wall thickness of the artery).