Subcutaneous cardiac rhythm management with disordered breathing detection and treatment

• US 20050107838A1
• Filed: 08/17/2004
• Published: 05/19/2005
• Est. Priority Date: 09/18/2003
• Status: Abandoned Application

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Lovett, Eric G., Stahmann, Jeffrey E., Hartley, Jesse W., Lee, Kent, Ni, Quan
• Application Number:
  US10/920,549
• Publication Number:
  US 20050107838A1
• Time in Patent Office: Days
• US Class Current: 607/17
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61B 5/4815 Sleep quality
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61N 1/3601 of respiratory organs
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

A lead system, coupled to an implantable device, is configured for subcutaneous, non-intrathoracic placement relative to a patient'"'"'s heart. Cardiac activity detection circuitry is coupled to the lead system and configured to detect cardiac rhythms. Disordered breathing detection circuitry is coupled to the lead system and configured to detect disordered breathing. One or both of cardiac therapy circuitry and disordered breathing therapy circuitry may be coupled to the lead system and configured to delivery therapies to treat disordered breathing. Such therapies include cardiac pacing, diaphragmatic pacing, and hypoglossal nerve stimulation therapies. A patient-external respiratory device, such as a positive airway pressure device, may be configured to deliver a disordered breathing therapy. One or more of a patient-internal drug delivery device, a patient-external drug delivery device, or a gas therapy device may be employed to treat disordered breathing.

Claims

1. A system, comprising:

a lead system configured for subcutaneous, non-intrathoracic placement relative to a heart of a patient; and

an implantable device, the implantable device comprising cardiac activity detection circuitry and disordered breathing detection circuitry, the cardiac activity detection circuitry coupled to the lead system and configured to detect cardiac rhythms, and the disordered breathing detection circuitry coupled to the lead system and configured to detect disordered breathing.

2. The system of claim 1, wherein the implantable device further comprises cardiac therapy circuitry coupled to the lead system and configured to deliver a cardiac therapy to treat detected disordered breathing.

3. The system of claim 1, wherein the implantable device further comprises disordered breathing therapy circuitry coupled to the lead system.

4. The system of claim 1, wherein the disordered breathing therapy circuitry comprises circuitry to coordinate delivery of a diaphragmatic pacing therapy.

5. The system of claim 1, wherein the lead system further comprises a hypoglossal nerve lead, and the disordered breathing therapy circuitry is coupled to the hypoglossal nerve lead and comprises circuitry to coordinate delivery of a hypoglossal nerve stimulation therapy.

6. The system of claim 1, further comprising a patient-external respiratory device configured to deliver a disordered breathing therapy to the patient.

7. The system of claim 6, wherein the respiratory device comprises a positive airway pressure device.

8. The system of claim 6, wherein each of the implantable device and the respiratory device comprises communication circuitry configured to facilitate communication between the implantable device and the respiratory device.

9. The system of claim 6, further comprising a patient-external processing system communicatively coupled to the implantable device and the respiratory device, the processing system configured to cooperate with one or both of the implantable device and the respiratory device to coordinate one or more of patient monitoring, diagnosis, and therapy.

10. The system of claim 1, further comprising one or both of a patient-internal drug delivery device or a patient-external drug delivery device.

11. The system of claim 1, further comprising a gas therapy device.

12. The system of claim 1, wherein the disordered breathing detection circuitry comprises an accelerometer configured to detect the patient'"'"'s respiration.

13. The system of claim 1, wherein the disordered breathing detection circuitry comprises a transthoracic impedance sensor.

14. A method, comprising:

detecting cardiac activity of a patient from subcutaneous, non-intrathoracic locations;

sensing, from one or more subcutaneous, non-intrathoracic locations, one or more physiologic parameters associated with respiration of the patient; and

determining presence of disordered breathing using the sensed one or more physiologic parameters.

15. The method of claim 14, further comprising delivering a cardiac therapy in response to determining presence of disordered breathing.

16. The method of claim 14, further comprising delivering a disordered breathing therapy in response to determining presence of disordered breathing.

17. The method of claim 14, further comprising delivering a diaphragmatic pacing therapy in response to determining presence of disordered breathing.

18. The method of claim 14, further comprising delivering a hypoglossal nerve stimulation therapy in response to determining presence of disordered breathing.

19. A system, comprising:

means for detecting cardiac activity of a patient from subcutaneous, non-intrathoracic locations;

means for sensing, from one or more subcutaneous, non-intrathoracic locations, one or more physiologic parameters associated with respiration of the patient; and

means for determining presence of disordered breathing using the sensed one or more physiologic parameters.

20. The system of claim 20, further comprising means for delivering a disordered breathing therapy in response to determining presence of disordered breathing.