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Drug coating providing high drug loading and methods for providing same

  • US 20050112195A1
  • Filed: 09/23/2004
  • Published: 05/26/2005
  • Est. Priority Date: 09/26/2003
  • Status: Active Grant
First Claim
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1. A dosage form comprising:

  • a core comprising a first drug; and

    a coating comprising a second drug, hydroxypropyl cellulose, and a water soluble film former comprising hydroxypropyl methylcellulose, copovidone, a film-forming agent that forms a solid solution with the second drug, or blends thereof;

    wherein the second drug comprises an insoluble drug present in the coating in an amount ranging from about 60 wt % to about 97 wt % based on the total weight of the coating, and the water soluble film former accounts for about 3 wt % to about 15 wt % based on the total weight of the coating.

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